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This Is MS: Tremor

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 Research: Keppra (Levetiracetam) shows Promise Against Tremor

TremorIntention tremor (or cerebellar tremor) is a common symptom in MS patients. It is characterized by a slow, broad shaking that occurs at the end of an intended movement. Of course, this can have a major impact on quality of life.

A new study examined the effect of the oral anticonvulsant drug Levetiracetam (better known by its brand name of Keppra (r)) on 11 MS patients with intention tremor. Happily, administration of Keppra was associated with an improvement in both subjective and objective tests. Furthermore, the degree of improvement was not associated with the underlying multiple sclerosis disease severity or duration.

Of course, this trial was small, short, and open-label (no placebo arm), so the findings must be considered promising but preliminary. However, given the ready availability of Keppra and the difficulty in managing tremor, this is an interesting study to discuss with one's doctor when suffering from this particularl symptom of MS.

Click "read more" for the study abstract.


Posted by Administrator on Monday, May 22 @ 04:59:57 EDT (3028 reads)
(Read More... | 3194 bytes more | Research | Score: 4.33)

 Deep Brain Stimulation for Treating Tremor

Tremor

A promising, yet seemingly drastic new treatment option being investigated for tremor...

"...A new therapy, called deep brain stimulation (DBS), is demonstrating in research studies that it may provide an excellent way of controlling dystonia and tremors...

Deep brain stimulation involves putting the tip of a hair-thin wire down inside the brain in a special area that controls movement. The wire then runs up through a small hole in the skull and under the scalp down to a little device implanted under the collarbone. The device, called a neurostimulator, sends tiny electrical impulses down the wire into the brain. The person can turn the DBS on when needed, and turn it off during sleep (when tremors are less)."


Posted by Administrator on Monday, May 24 @ 01:57:59 EDT (1760 reads)
(Read More... | 6503 bytes more | Score: 0)

 Research: Marijuana does not help Tremor

Tremor

This small study showed that cannabis (Marijuana) did not have any positive effect on tremor experienced by MS patients. In fact, the commentary is somewhat funny (finger-tapping test was slower in those on marijuana, feel-good was higher...)

"BACKGROUND: Disabling tremor is common in patients with multiple sclerosis (MS). Data from animal model experiments and subjective and small objective studies involving patients suggest that cannabis may be an effective treatment for tremor associated with MS...

RESULTS: Analysis of the data showed no significant improvement in any of the objective measures of upper limb tremor with cannabis extract compared to placebo...

CONCLUSIONS: Cannabis extract does not produce a functionally significant improvement in MS-associated tremor."

Click "read more" for the full abstract


Posted by Administrator on Saturday, April 17 @ 15:33:28 EDT (1361 reads)
(Read More... | 3223 bytes more | Research | Score: 1)


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