Here's a story on a new drug called LGD5552 that prevents EAE-- the purported animal model of MS. Unfortunately, many drugs have a great effect on EAE but do not work in humans, so all we can do is hope that one of these will transfer to humans and be just as effective.

"...Bebo and his collaborators studied rats suffering from experimental autoimmune encephalitis, a commonly studied animal model for human MS that has been used for about 50 years. The researchers provided some of the animals with LGD5552 at the time of disease induction. A second group of animals received a related anti-inflammatory called prednisolone. The third group of animals went untreated.

While the untreated animals developed paralysis , prednisolone-treated animals suffered reduced effects and LGD5552-treated animals remained free of weakness. In addition, the LGD5552-treated animals maintained their body weights, while other animals in the study lost weight. Animals that received the test drug also didn't develop inflammatory lesions in the spinal cord as did other animals. These lesions also are common in humans suffering from MS..."

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