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 | BioMS expands MBP8298 trial to RRMS patients |
 BioMS, developers of the experimental MS therapy known as MBP8298, have now received medical regulatory agency approval to begin a Phase II trial (out of III necessary for approval) to determine the effects of the drug on patients with the relapsing-remitting form of multiple sclerosis. They currently have a Phase III trial investigating the drug's efficacy versus secondary progressive multiple sclerosis-- a noble achievement given the relative dearth of pipeline treatments for that more insiduous form of the illness.
The trial will take place over one year and enroll approximately 200 patients, with the primary goal to ascertain efficacy and safety of MBP8298 versus placebo. Further, the patient pool is selected to be of the type with the specific immunity genes known as HLA-DR2 or HLA-DR4-- which, according to the company, 75% of the MS population has. The reason for this restricted enrollment set is that MPB8298 works by specifically targeting those particular immune system components, and the company believes the drug will be of highest efficacy in the group that has that particular genetic makeup. Unlike many of the drugs now in development for MS, MBP8298 is administered intravenously.
Click "read more" for the company's press release on this news item...
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Posted by Administrator on Tuesday, May 16 @ 15:22:29 EDT (3123 reads)
(Read More... | 4798 bytes more | Score: 4.33)
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