This study posits that mood disfunction, specifically depression, is not related to physical disease progression.
"Long-term development of psychological deficits in disability-free early multiple sclerosis (MS) was evaluated in 27 female patients over a period of 7 years and compared with healthy controls. Physical and cognitive parameters deteriorated significantly but not depression scores..."
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Cognitive, but Not Mood Dysfunction Develops in Multiple Sclerosis during 7 Years of Follow-Up.
Haase CG, Tinnefeld M, Daum I, Ganz RE, Haupts M, Faustmann PM.
Department of Neurology, University Hospital Essen, Essen, Germany.
Long-term development of psychological deficits in disability-free early multiple sclerosis (MS) was evaluated in 27 female patients over a period of 7 years and compared with healthy controls. Physical and cognitive parameters deteriorated significantly but not depression scores. In particular, the self-assessed somatic complaints remained non-similar between patients and controls. This indicates that although depression is clinically relevant and frequent in MS, in contrast to cognition it is not related to physical disease progression. Copyright 2004 S. Karger AG, Basel
PMID: 15273430 [PubMed - as supplied by publisher]
Eur Neurol. 2004 Jul 22;52(2):92-95. Related Articles, Links