This double-blind study showed the effectiveness of Viagra (sildenafil citrate) in treating erectile dysfunction in men with multiple sclerosis. Seems like an obvious conclusion, but studies are generally a good thing to have...one interesting item to note in the abstract is the large response to placebo!

"OBJECTIVE: Identifying and effectively treating erectile dysfunction (ED) can result in an improvement of the quality of life (QoL) in men with multiple sclerosis (MS)...CONCLUSION: Sildenafil treatment for ED in men with MS was effective and well tolerated, and resulted in significant improvements in both general and disease specific QoL variables."

Click "read more" for the full abstract...

Full Study Abstract

A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis.

Fowler CJ, Miller JR, Sharief MK, Hussain IF, Stecher VJ, Sweeney M.

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, Mailbox 71, Queen Square, London WC1N 3BG, UK. cfowler@ion.ucl.ac.uk

OBJECTIVE: Identifying and effectively treating erectile dysfunction (ED) can result in an improvement of the quality of life (QoL) in men with multiple sclerosis (MS). METHODS: This randomised, double blind (DB), placebo controlled, flexible dose study with an open label extension (OLE) assessed efficacy, QoL, and safety of sildenafil citrate in men with MS and ED. Overall, 217 men received sildenafil (25-100 mg; n = 104) or placebo (n = 113) for 12 weeks. Efficacy was assessed by the International Index of Erectile Function (IIEF) questionnaire that includes questions on achieving (Q3) and maintaining (Q4) an erection as well as a global efficacy question (GEQ). QoL was also assessed. RESULTS: After 12 weeks, patients receiving sildenafil had higher mean scores for IIEF Q3 and Q4 compared with those receiving placebo (p PMID: 15834030 [PubMed - in process]