I took 4-AP-3-MeOH for approx a year, and had pretty similar results to the 4-AP, But it was a Much more pleasant to take. I felt very well on it.
Unfortuately, the compunder I was getting it from at the time, charged me way too much to have it formulated, & that is why I switched back to 4-AP.
The highest dose I ever took of the 4-AP-3-MeOH was 6mg every 4 hours x 4 times daily. I should have tried a higher dose to see if I had a better result, but the cost prohibited it at the time.
Now days, I'm only interested in venoplasty for CCSVI, which I have had 3 times and is the Best remedy of all for MS. IMHO