I have just finished my 3rd week on fampyra. I noticed an improvement in my walking in the first week and my ability to stand unassisted by the end of the 2nd week. I haven't done much this week due to other family issues but will get back working on further improvements next week. My neuro said that if positive changes weren't visible within the first few weeks it probably wouldn't work at all. I think it's great stuff. I have not suffered from any of the listed possible side effects.