.....................claiming no pain no gain and ignoring a strain.....that later turns into a big problem..
Stratton finds that by addressing these three phases you are most likely to killl the Cpn completely and prevent and reservoir for reinfection. In fact, he says that once immune cells are cleared of Cpn, they actually are more resistant to Cpn infection.
If you say of course this is why David recommends small short pulses at first, I'll say good. I figured it out. I like to know things like this. It keeps me honest...as in, I will not overdo the flagyl thinking to tough it out so I can get done faster because understanding the physiology I will 'get' that it won't help to overdo it. That would be me.
mrhodes40 wrote:but here I'm making a guess based on my understanding of physiology: locally where the cell died and the immune system is actively taking it apart which results in this endotoxin release, you have inflammation (cytokines, macrophages) which is how the body gets immune cells in that location. This is ordinary cleanup.
Inflammation results in stimulation of remyelination ( http://brain.oxfordjournals.org/cgi/con ... /128/3/528 ) . My theory was if the pulses are too close, you hamper the repair process as the ongoing battle results in peroxynitrates and other toxic elements being released to perfom the cleanup and hence the newly stimulated remyelination and progenitor cells would be hampered by the presence of the peroxynitrates and other toxic elements of the cleanup operation. It's a theory that might indicate why a person needs to have small pulses early on when the load is great and why it is not a time to tough it out but to respect the repair and cellular processes going on and lay off if you feel punky.
You know if you read the link I put in there it is a brilliant reason to be annoyed with the immunosuppression model of treatment..........
Does physical activity cause an overdo also? Like if you are pulsing and you go on a bike tour (HAH! didn't know I was a comedienne did you?)
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