I hope you get this.
My abx is: Rifampin, Doxy, Azithromycin, and pulsed Flagyl. I also take Avonex about every 9 or 10 days. Yes, my dr. wants my LFT just about every month . I take ALL on their prescribed schedule. This means Rif 2xD, Doxy 2xD, Azith 3x week, Flagyl 5 D every 3 weeks (this time I started 1 week early- working really well). This week I will be taking all of them when I get LFT. I have done this before and shown all only slightly elevated. They are most elevated after Avonex- big spike. More and more I maintain I would give up Avonex before abx at this point.
When you come to a fork in the road, take it. Yogi Berra
Dr. Powell finds most patients improve on a standard combination antibiotic protocol for Cpn. Rheumatologist have apparently been using doxycycline for many years with success for inflammatory arthritis but there is evidence that using doyxcycline in combination with rifampin is even more effective. Some patients plateau after about 8 months of treatment he has found variations in the treatment protocol have made a difference. One protocol he uses involves the use of NAC 600 mg twice daily, INH 300 mg once daily before breakfast, and metronidazole 500 mg twice daily pulsed with 5 days on and two weeks off. It is essential to start each agent separately and gradually increase the dose over weeks or months as tolerated. The use of Vitamin C 500 - 1000 mg four times daily (the half life of vitamin C is 30 minutes and little remains after 3 hours) to offset the release of toxins during therapy. B6 is important to control INH related peripheral neuropathy. Monthly laboratory evaluation of AST, ALT, Cr, and CBC are recommended for all who engage in this protocol. It is not uncommon for liver enzymes to show a mild elevation during the initial stages of treatment. Antibiotic therapy should be temporarily discontinued during periods of toxicity, should it arise. He emphasized the importance of insuring that yeast and fungal infections do not overgrow during protracted antibiotic use. He recommends the use of acidophillus, nystatin, diflucan, oregano oil, and/or grapefruit seed extract as needed to prevent secondary opportunistic infection during treatment.
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