This is my first post here, I have been ill for many years with "something" infectious which includes (or included at some point in time) Lyme, but which is not limited to just Lyme. I suspect chlamydia pneumonia to be one of the culprits as well (only serotested once IgG 1/64).
My symptoms over the years have been truly horrendous like heart arrhythmia, heart and breathing stopping during the night (several times a night for years), rotating vertigo attacks, excrutiating headaches, eyes extremely sore, eyeballs aching, light sensitive, unable to read, pain in all kinds of places, joints, muscles, along spine, neck, swollen sore glands, I could go on forever
I have been taking abx (several kinds, several combos + antiprotozoans) for the last 6 years (yes 6 years!). I have seen some spectacular improvements in some of my symptoms (like heart and vertigo) but "war is not over" yet.
I was aware of Stratton and the work they conduct at Vanderbilt Uni but I sort of assumed I was taking so many abx I was probably covering chlamydia as well, and I probably was to some extent.
Like JimK, I belong to the Yahoo list Infection and Inflammation and when David Wheldon's articles were discussed, I became interested in Chlamydia again.
Actually, what caught my attention was the fact that both David and Vanderbilt insisted on the importance of the imidazoles in the tx of chlamydial infections. I had ALWAYS had dramatic improvements after using metronidazole or tinidazole, especially in brain functioning. Unfortunately I always seemed to hit a wall after a few days' use of an imidazole (head exploding for eg), as well as a very toxic feeling all over.
I am sure I will write more later (I have to limit my writing bec of very sore eyes) but right now I would like to ask here some questions that I just asked on the I&I list:
Many of us on long term abx take probiotics in an attempt to replenish our gut flora. I have often wondered what the impact of such an intervention might be.
Could the probiotics we take be "using up" our abx as well as causing us to have to deal with constant (much worsened) lysis of much more bacteria than would be otherwise necessary?
Would a compromised gut mucosa (leaky gut) not be the "efficient barrier to endotoxins" that they describe in the article?
Might we be doing ourselves a favour by NOT supplementing with probiotics? Would we be gaining more benefits from making do with "selectively deplenished" gut flora as a result of abx taking?