I think it's accurate to say that there have been problems replicating the results of finding CPn in the CSF of those with MS.
No (my fault), that's not what I meant by "duplicating the results". What started the whole thing was that a man who was given antibiotic treatment went fairly suddenly from being in a wheelchair to walking!
THAT'S the "duplication" they haven't been able to produce again. NOT whether they are detecting CpN or not. Almost 70% of the population tests positive for Cpn.
Sorry, my fault. I wasn't being clear. I just "assumed" that everybody knew what had "initiated" him looking into CpN in the first place.
The below is what "initiated" Dr. Sriram's research into CpN and MS in the first place. THAT'S what I was referring to. They have not been able to duplicate the same type of rapid "recovery" again.
And yes, there is evidence that minocycline (and/or other antibiotics) helps. I'm not debunking that at all.
....Sriram's research began in July 1996, when a seriously ill deputy sheriff from Bedford County was admitted to Vanderbilt University Medical Center.
Five months after he developed symptoms of MS -- vision problems and tingling down his left side -- Brad Lamons was unable to move either leg or his left arm, and he was having difficulty swallowing.
"I was scared," said Lamons, 26, of Tullahoma. "I was going down so fast that within a week or so I'm afraid I'd have been on a ventilator."
When tests of his spinal fluid came back positive for chlamydia, Sriram put him on an aggressive, 18-month-long course of powerful antibiotics.
Several weeks later, with the help of a physical therapist, Lamons was walking again.
He has continued to improve, without a relapse, for nearly three years, though he can no longer work as a deputy because he tires easily. Lamons said he hopes to train for a job in computer-aided drafting.
Inspired by Lamons' dramatic recovery, Sriram, a professor of neurology who directs Vanderbilt's MS center, began looking for chlamydia in other patients with MS. ....
....In an interview, Sriram cautioned against drawing too enthusiastic a conclusion from the Vanderbilt study or from Lamons' anecdotal experience. ...."