I am in the rare group with virtually no reaction to many of the protocol's components, so I don't speak from experience here.
The NAC is, yes, important. But no one says you have to do what I did and take the whole protocol, vitamins and adjuncts included, together on the first day and every day thereafter. The idea is to work up to it, always with an eye toward not developing resistance, of course.
If working up to it means one NAC pill today and one next week and two the week after that, so be it. Reaction means bacterial kill, so you have some comfort in that. Take more when you feel able.
The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi