I just finished my 4th flagyl pulse on Wednesday May 21, 2008.
This flagyl pulse was definitely the most challenging thus far. Prior to this one flagyl didn't cause me too much problem. I always felt worse while taking it but it wasn't too bad. This time was a little different. I definitely knew I was taking it! I woke up every morning with body aches that subsided after several hours. I took Epsom salt baths, whirlpool, massage, Emergen C etc and all helped alleviate it some. I also have feet pain that I have had since this past summer. But during the pulse it was worse. I had an upset stomach more often than not and some waves of nausea. Ginger helps this some. I found it difficult to get in all the NAC during this week because taking any more pills didn't help the situation! One of the biggest things I find with flagyl is the fatigue I experience. I am fortunate not to have much during the off-flagyl time but it is definitely there with flagyl. I do have to comment that when I first started flagyl this week I was finishing a prescription of Levoquin for a UTIi. They overlapped 2 days. So one more antibiotic this time.
I did experience the "blues" this time also. I have a prescription for clonazepam and that helps take the edge off without affecting anything else.
I also noticed an increase in heart rate during this time. Could feel my heart "pounding" at times. Not so much after finishing flagyl. Also, have noticed the tremor in my hand has returned. It had left for a little while but seems to be back some.
I finished the flagyl on Wednesday. By Saturday the tiredness had improved enough to go shopping with my 14 year old daughter, which you can imagine is not a short trip! I did okay with a few rests in between.
I keep a journal beside my bed and jot down a few things at night. I noted that this was the toughest pulse thus far. Not so much that I would change the length of the pulse or take something else. But I had enough reaction to state in my journal that if I had any doubt that this was doing something, this week took that doubt away.
Interestingly, I had an appointment with my GP for my foot pain to see if there was anything that we could do to help it. He asked me if I thought this protocol was still working positively for me. At the time I started this he was willing to go along with it and learn everything he could about it. But wanted me to be seen at Vanderbilt for the oversight of the protocol itself. He is also a family friend so sees me in social situations. He told me that he has seen a change in me. That I am more "with it", cognitively, don't have trouble expressing myself, seem to be doing really well. I think it is significant that he sees positive changes because he sees me enough to note changes but not every day where he may not recognize things. Even more interestingly is that he told another patient of his about this protocol and referred him to Vanderbilt. I think that says a lot!
All in all, it has been a little more challenging this pulse but reassuring also that I am "killing the bugs!"