jdamon wrote:Will these side effects ever go away?
I understand all too well what you're going through. I've been on Avonex for almost 5 years now. I also had side effects much longer than what Biogen states is the "typical" time period. For me, they lasted about 1.5-2 years but have now reached a level where they are negligible. Now, I just plan on taking it easy the day after my injection as my energy levels are much lower than normal.
I also tried using Tylenol for dealing with the side effects as per Biogen's literature. However, I found that Tylenol was not at all helpful and had one of the worst fevers that I can recall ever having after my first injection. My doctor's nurse suggested I try ibuprofen instead and this has worked for me. During the first year or so, I would start taking ibuprofen about 12 hours before my injection followed by 24 hours after my injection. The dose I used was 600 mg of ibuprofen about every 6 hours always with food. Fortunately, I'm now to a point where I can get by with just one 600 mg dose at the time of my injection although sometimes I need to follow this up with another 400 mg about 8 hours later. In addition, I discovered that I get by best if I take my injection during the day rather than try to "sleep through the side effects" since that never really worked all that well (I often woke up in the middle of the night with a fever, chills, or shakes). However, I found that I'm usually ok during the day and sleep all right if I inject around noon.