ga_kristy wrote:sorry this may be sort of a repeat of anther question.
Does everyone get side effects like the flu and chills etc. from avonex? my son starts soon, but I do think the Dr. wants us to choose between this one and the beta one. But leaning toward this one due to the once a week thing. one the other hand, the side effects do sound aweful.
We present the cases of two female patients diagnosed with relapsing-remitting multiple sclerosis (RRMS) who developed inflammatory musculoskeletal manifestations, following IFN-beta therapy.
Our literature review revealed an additional six cases of onset of inflammatory arthritis in MS patients receiving IFN-beta.
A literature search revealed an 11% (5% clinically overt) overall incidence of de novo thyroid dysfunction in IFN-beta-treated MS patients, mostly autoimmune hyperthyroidism. (Large-scale comparative studies for IFN-beta-1a are not available at present). Specific treatment but not necessarily discontinuation of IFN-beta-1b therapy was required in most cases. Female gender, pre-existing thyroid autoimmunity, and family history of thyroid disorders are presumable risk factors for thyroid dysfunction de novo during IFN-beta-1b treatment.
Post marketing studies of Interferon-beta (IFNbeta) therapy<br /> in multiple sclerosis (MS) have demonstrated surprisingly high rates of hepatotoxicity. Grade 3 hepatotoxicity (AST and ALT > 5 to 20 upper limit normal) or higher has been observed in as many as 1.4% of MS patients on IFNbeta.
Users browsing this forum: No registered users