Thanks for responses. I often wonder if I am even really aware of how much Avonex has changed my life. I have considered taking a break, but I hear that going back on will be like starting over--ugh!! I usually inject on Friday afternoon and try to veg on Saturday; however, I often have meetings on Saturdays. I am also very active in my church, so Sundays are busy days--good days, but busy! I have given up quite a bit of responsibilities on Sundays because otherwise, it is impossible to cope. The good news is the my husband is wonderful. He is patient and understanding beyond belief. The truth is, for three years, I told NO ONE about my diagnosis--not even family. A few months ago I finally began telling people, and it is amazing how freeing it has been. I don't have to hide the fact that I feel like crap sometimes. What was I thinking? I didn't want sympathetic looks, worried parents, suggestions on how to cope etc. So far, I have not regretted being open about MS. I still don't participate in MS walks, etc. Maybe one day I will.