What are the benefits of Betaseron?

A board to discuss the Multiple Sclerosis modifying drug Betaseron

What are the benefits of Betaseron?

Postby David1949 » Wed Aug 25, 2010 2:55 pm

From what I understand Betaseron and similar drugs are touted as reducing the number of relapses. Is that correct or can they slow disease progression as well?

I have never had relapses in my 15 years with MS so I never started taking any of those drugs.
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Re: What are the benefits of Betaseron?

Postby NHE » Wed Aug 25, 2010 3:27 pm

Hi David,

David1949 wrote:From what I understand Betaseron and similar drugs are touted as reducing the number of relapses. Is that correct or can they slow disease progression as well?

I have never had relapses in my 15 years with MS so I never started taking any of those drugs.


I should note that I'm not recommending interferon-beta. If what you've been doing for the last 15 years is working for you, then stick with it. If you haven't been doing anything special, then you might want to take a look through both the Diet and Natural Approach forums for some ideas that can easily be incorporated into a daily routine.

To answer your question, I posted some data from Avonex's doctors prescribing information pamphlet a while back.

http://www.thisisms.com/ftopicp-60622.html#60622

These graphs show that Avonex does appear to have a mild affect on disease progression. Note that the numbers that Biogen (and almost any other pharmaceutical company) uses are relative percentage differences. In effect, the absolute percentage difference is 13% between the treatment group and the placebo group. However, using relative percentages, the difference is 37% which is the number for effectiveness which is usually published for effectiveness against disability progression. As you may have guessed, I'm not all that thrilled with the use of relative percentages in medical studies.

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Postby Vivianne766 » Wed Aug 25, 2010 3:34 pm

I was on avonex for 4-5 years. It did not do much and eventually I started having relapses. Then I went on Inetrferon Beta . Another 5 years .
Did not do much. but that was the only thing I could do.
I am waiting to get liberated. So I am quiting my meds.
I think my doc. was only a sales rep. for these drugs.
She wanted me to go on chemo and I said no.
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Scary doctor

Postby Rebecca » Sun Oct 10, 2010 1:31 pm

Wow, I'm with you. I think some docs do push these drugs too much. I'm glad you said "NO" to chemo. Ridiculous in most cases.
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Re: What are the benefits of Betaseron?

Postby Slumby » Fri Oct 14, 2011 4:38 pm

If not the drug-pusher thing, I feel like a test subject. I once was denied betaseron because I was told by the doctor thatt she already had another patient on that.
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