Personally I don't take any of the DMD drugs. But a woman I know who got MS about 25 years ago had this to say. She was on Betaseron since she was dxed. She said it was the only thing that kept her out of the hospital. Recently her doctor took her off of it because her latest MRI showed no lesions. She is still somewhat disabled but has no lesions and she hasn't had any new problems since being off Betaseron. I'm not a fan of DMDs but thought I should publish this just for the record. BTW I think this result is not typical.
Edit- Betaseron was introduced in 1993 so I guess she was on it since then.