I just came home from the MS Research day seminar, organised at the Whitechapel Hospital in London by Professor G. Giovannoni. CCSVI was briefly touched upon by one of the speakers, who presented a generally fair overview of Zamboni's research commenting that it is very novel and interesting, only to shoot the theory down a few minutes later based on the preliminary results of a CCSVI trial at Charité, Berlin.
I searched TIMS and did a quick google search on the trial but couldn't find anything, so i post here the information that was presented to us in the seminar. Obviously i haven't seen a research paper or announcement by the team conducting the trial therefore the information below comes with a disclaimer.
According to the speaker, a team in Charité, Berlin has tested 40 PwMS and 10 healthy controls trying to replicate Zamboni's findings of venous malfunction. No information was presented about how the trial was conducted, so i don't know how they defined whether a patient has/has not CCSVI. The trial is still ongoing (so more people are being tested), but in the 40 MS patients tested so far none was found to have CCSVI.
Has anyone heard anything about this trial? Maybe the German members of the board?
I am personally not 100% convinced about CCSVI, i still thought however that the way it was presented today was not objective, which is the minimum i would expect from professionals conducting medical research and whose job is to look for facts. The possibility of false negatives at the Charite trial was not mentioned,nor were the other replicating studies going on at the moment, despite the fact that there was a reference to two deaths in California (surely if you are aware that people 'have died' from performing the surgery you must be aware that researchers outside Italy have also identified the problems Zamboni did?).
I could go on talking about the way CCSVI was presented however i believe there is enough momendum behind the theory so it is almost irrelevant how it is presented by doctors/societies- the truth will pan out quite soon.
By the way the seminar was otherwise very well organised and informative, so i don't mean to undermine the effort put in by the organisers, i am only commenting on the part that had to do with CCSVI and is relevant to this post.