Alright, the Buffalo results are out.
56% correlation is far from the 100% claimed by Zamboni.
I am trying to stipulate what this could mean:
(i) There is no causality effect between vein narrowing and MS. Narrowing occurs as a symptom of the disease (like itching, blindness and else) for half of the patients.
(ii) OR, CCSVI is a factor leading to MS. The fact that only 50% have it coincides with the statistic that 50% go into Phase 2 (Secondary progressive), while the rest are stabilizing as the veins open after a while. So the one who still have narrowing (say after 10-15 years from disease discovery) are on a bad course.
I still don't see how MS could cause CCSVI considering that CCSVI manifests itself in so many ways. I mean, if CCSVI was simply the cell walls of the vein were larger than usual and hurt blood flow then ok, maybe, but we have CCSVI cases where people have veins pinched by bones, cases where people have jugular veins that are too short, cases where the veins are too wide, cases with missing veins or misfunctioning valves, etc. It doesn't make sense to me that MS would cause a variety of competely different scenarios that lead to the end problem of reflux of blood into the brain.
I find the 55%/62% numbers a little discouraging with the 80% being a little more comforting. We'll just have to see how this plays out with additional studies.