Of course such data might be interpreted to mean CCSVI develops as MS progresses but if one accepts the consensus opinion of the vascular researchers that the vascular malformations that constitute CCSVI are congenital, then the hypothesis that CCSVI makes MS worse (as opposed to the hypothesis that MS makes CCSVI worse) would be the best one.
This is one more solid reason that one would want CCSVI resolved asap.
Hi Direct-MS! Nice to see you here in the discussion. Some of the venous malformations Dr. Dake has been noting are most certainly congenital- this is from his presentation in Hamilton-
Lesion etiology is non-specific (congenital/hereditary, osseous impingement, arterial compression, post-inflammatory, arachnoid granulation, etc., alone or in combination
He has seen a variety of issues which he believes are congenital or hereditary....but not just one specific malformation. We may find that some people can tolerate their particular malformation until an event happens (EBV infection, injury, stress related incident, endothelial disruption) when the reflux becomes exacerbated. My husband lost his peripheral vision at 12...no doctor could figure out why...he had drusen, but they suddenly blocked his vision. It wasn't for another 30 years to his MS diagnosis. Obviously, there was a slow and steady progression.
I agree, let's take care of the venous blockage, get the blood flowing and then figure out the rest of the puzzle. No matter which comes first- venous reflux is not good for the brain and spine.
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
dual stents placed 5/09
CCSVI in MS