Link between Obesity and CCSVI

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Link between Obesity and CCSVI

Postby Nunzio » Sat Feb 13, 2010 9:59 am

A recent paper showed a 2 fold increase to develop MS if the person was obese as a teenager. Another medical condition associated with obesity is Pseudotumor Cerebri which is a condition where the intracranial pressure increases. Incidentally the initial damage is done to the optic nerve if not treated.
I came across a paper published in 2007 to understand the reason

"Conclusions.: These data support the hypothesis that central obesity raises intra-abdominal pressure, which increases pleural pressure and cardiac filling pressure, which impede venous return from the brain, leading to increased intracranial venous pressure and increased intracranial pressure associated with pseudotumor cerebri."

Now this might as well be applied to CCSVI.
I cannot find an explanation if MS was just an autoimmune disorder.

http://www.neurology.org/cgi/content/abstract/49/2/507
http://www.medpagetoday.com/Neurology/M ... osis/16922
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Postby Cece » Sat Feb 13, 2010 1:55 pm

Wow, good find. So carrying abdominal fat impedes venous return from the brain....
"However, the truth in science ultimately emerges, although sometimes it takes a very long time," Arthur Silverstein, Autoimmunity: A History of the Early Struggle for Recognition
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