Just googling endothelial disruption turns up some interesting articles.
"Blood-brain barrier disruption in multiple sclerosis"
"Exposure of endothelium to proinflammatory cytokines (IFN-g, TNF-a and IL-1b) interrupts the BBB by disorganizing cell-cell junctions, decreases the brain solute barrier, enhances leukocyte endothelial adhesion and migration as well as increases expression of class II MHC and promotes shedding of endothelial ‘microparticles’ (EMP). In this review we examine interactions between cytokines/chemokines, activated leukocytes, adhesion molecules and activated C EC in the pathogenesis of BBB failure in MS."
This is from 2003, without the CCSVI paradigm but looking at the vascular side of m.s. Again those adhesion molecules are mentioned. I am assuming proinflammatory cytokines would be what the body makes in response to viruses in general.
"However, the truth in science ultimately emerges, although sometimes it takes a very long time," Arthur Silverstein, Autoimmunity: A History of the Early Struggle for Recognition