1 - actual first line treatments are working and are safe... And no serious long term effects has ever been reported with interferon and copaxone.
Holy crap!! Where in the world did you come up with such an outrageous statement? Even aspirin can cause "long term effects." I've read tons of reports of the use of interferon beta for MS occasionally leading to liver failure and liver transplants. Google it.
It really upsets me when the MS meds are portrayed as practically harmless. They're very powerful, potentially dangerous drugs, with side effects that rival my worst MS episodes.
"Effective" is pretty vague - there's no way to test that on any individual. If I had been taking a "first line treatment" for the last 20 years, I'd be one of their most magnificent success stories. But I haven't.
Sorry, for the grouchy mood... I'm sitting here with a cold that's finally beginning to kick my ass tonight. I did manage a whole day of work today before I gave in to it, however - I don't take MS meds, so I'm not already sick when I get hit with an illness.