Corelation between lesions and type of CCSVI defect
Corelation between lesions and type of CCSVI defect
My MRI scan shows lesions in both brain and spine. Assuming, CCSVI is applicable to me, does it mean I have problems in both jugular as well as azygos veins?
- gibbledygook
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Makes sense to me...that lesions would only be level or higher than where the stenosis occurs...it offers a good explanation for why some people get hit with spinal lesions and others only brain...was there ever an explanation for that in conventional m.s.-as-strictly-autoimmune theory?
"However, the truth in science ultimately emerges, although sometimes it takes a very long time," Arthur Silverstein, Autoimmunity: A History of the Early Struggle for Recognition
Makes me feel a bit better that azygos might not be involvedgibbledygook wrote:I have spinal and brain lesions but Professor Dake could only find stenoses, albeit rather large one in both jugular veins.
But still does not seem logical going by CCSVI theory. If I have lesions in spine, it would be fair to assume that there is reflux happening back to spine. This can happen only if there is stenosis (or any other defect in azygos). Just wondering ...
- Salvatore24
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- ozarkcanoer
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gibbledygook:
So this has plagued me too, is lesion/stenosis location related, or predictive of each other ???
sou:
And Dr Sclafani (thanks!!) made comments yesterday at TIMS, that the big issue is rate of flow. So I imagined a normal person having a complete circulation exchange in 4 min like a roaring river, while mine took 8 min like a lazy river, because of the stenotic beaver damn in neck! I'm surprised my heart didn't pop or poop out.
Explains the roating pulse noise that I and others have reported. That has stopped for me. This past week I turned a curve, no more shoulder pain, and walking better!
Ditto on me, all stenosis collarbone and above for me, but spine plumb full of lesions (C2, C3-7, T3-4, T6, T12) Brain: Dawson's fingers, old lesions and black holes, no new lesions since 2004.I have spinal and brain lesions but Professor Dake could only find stenoses, albeit rather large one in both jugular veins.
So this has plagued me too, is lesion/stenosis location related, or predictive of each other ???
sou:
sou - thank you! So stagnant blood at any point can cause lesions, or the activated T-cells are just released throughout the CNS and cause damage regardless of stenosis location.blocked IJV leads to increased load and altered haemodynamics throughout the whole vertebral plexus
And Dr Sclafani (thanks!!) made comments yesterday at TIMS, that the big issue is rate of flow. So I imagined a normal person having a complete circulation exchange in 4 min like a roaring river, while mine took 8 min like a lazy river, because of the stenotic beaver damn in neck! I'm surprised my heart didn't pop or poop out.
Explains the roating pulse noise that I and others have reported. That has stopped for me. This past week I turned a curve, no more shoulder pain, and walking better!
RRMS '95 SPMS '02 | CCSVI 10/09 | Adult stem cells 2012 | http://www.patientsforstemcells.org/
- ozarkcanoer
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I have about 40 brain lesions and as far as I know 0 spine lesions.
Talk of a "roaring pulse noise" caught my attention. When my fatigue and headache come on me my head is hot and it pulses and I can hear it very loudly. It is so loud that I can nod my head at the beat. It is horrible. It just seems that CCSVI has to account for this somehow. These are the kind of symptoms that are most difficult to describe.. I'm almost ashamed to try to tell my neuro lest I be called neurotic or crazy. Maybe I'm not so crazy after all. Boy do I want to go to BNAC and get the US and MRI/MRV.
Thanks for listening to my rant .
ozarkcanoer
Talk of a "roaring pulse noise" caught my attention. When my fatigue and headache come on me my head is hot and it pulses and I can hear it very loudly. It is so loud that I can nod my head at the beat. It is horrible. It just seems that CCSVI has to account for this somehow. These are the kind of symptoms that are most difficult to describe.. I'm almost ashamed to try to tell my neuro lest I be called neurotic or crazy. Maybe I'm not so crazy after all. Boy do I want to go to BNAC and get the US and MRI/MRV.
Thanks for listening to my rant .
ozarkcanoer
- suze
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If you look at Zamboni's paper, Zamboni et al Dec 2008 "Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis" Figure 3, it outlines the 4 different patterns of venous malformation that he found.
They all variously alter the drainage of different veins, and it shows the drainage of the azygous vein can be altered when stenosis is found in the jugulars. I assume this could cause spinal lesions, without the need for actual stenosis in the azygous.
They all variously alter the drainage of different veins, and it shows the drainage of the azygous vein can be altered when stenosis is found in the jugulars. I assume this could cause spinal lesions, without the need for actual stenosis in the azygous.
When I sleep, I unconsciously tend to push my head to the wall of the bed (I feel better). In this condition, I can feel the beats. Initially this was frightening.ozarkcanoer wrote:I have about 40 brain lesions and as far as I know 0 spine lesions.
Talk of a "roaring pulse noise" caught my attention. When my fatigue and headache come on me my head is hot and it pulses and I can hear it very loudly. It is so loud that I can nod my head at the beat. It is horrible. It just seems that CCSVI has to account for this somehow. These are the kind of symptoms that are most difficult to describe.. I'm almost ashamed to try to tell my neuro lest I be called neurotic or crazy. Maybe I'm not so crazy after all. Boy do I want to go to BNAC and get the US and MRI/MRV.
Thanks for listening to my rant .
ozarkcanoer
Maybe a bit off topic, but I believe CCSVI has given hope to lot of patients as:
- it is no longer a disease of unknown autoimmune disease (known devil is better than ...)
- lot of issues reported by MSers are generally dismissed in "in-your-head". CCSVI explains quite few of them convincingly.
I have no doubt, a lot of unknown about MS as the direction of research was completely in the wrong direction ...
- whyRwehere
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My husband was treated for ccsvi, but he has very few lesions, which have not increased since his diagnosis 8 years ago. They are not active and they are quite small. But he seems to be ppms.....perhaps there are lesions in other places, which are never searched for with the normal MS prescribed MRIs?
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