NZer1 wrote:Sounds to me like Pathology studies to show what does physically happen with PTA will be needed to take the guess work out of the equation.
If I understand correctly there isn't a way to measure the flows before, during and after PTA, and there is no way of knowing what is popping or tearing under pressure.
I WOUND NOT AGREE WITH THAT. i AM FAIRLY SURE THAT FOR THE MOST PART THE VALVES AND TISSUES CONNECTED TO MALFORMED VALVES ARE WHAT ARE STRETCHED AND TORN
I am guessing that until it is understood what re-stenosis looks like we are in the dark.
actually, i do not feel like i am in the dark anymore. i am fairly confident that I know what i am doing and how things are opened.
my problem is mostly in predicting who will respond to that treatment
** Pathology studies would have happened in the past to evaluate Angio in other areas of the Body for other reasons, is it something that crosses over to be accurate when working on Juggs and Azy?
pathology studies require either surgery or autopsy to get the tissue to do pathological studies. The good thing is that most patients with MS do not die at an early age.
I have always believed that the MS disease is too loose a term and that there are many, many subtypes of the disease and that the Progressive disease is the truest form. Studies on the Vascular involvement on this form in my humble opinion are where the greatest knowledge gain will be. If Pathology studies are used with the focus on the restrictions and pathways back to white and grey matter lesions that will be the inroad to knowledge. The methods of changing the flow issues will again be based on Pathology insights.
nigel, i am sure you are not a willing volunteer for such pathological studies. we want you to keep on living!!!