dania wrote:So far there is very little on peer reviewed literature. CCSVI is so very new.
From my first read, it was disappointing to read that the damadian group rejected, as controls, patients with abnormal spines without ms features. So they did not control for the variable they were studying. So we do not know whether the CSF flow disturbance was more common in patients with MS than with others with a history of whiplash injury, vigorous dancing or hammers landing on the head. we only know that patients with MS commonly had spinal abnormalities and that patients with MS have slowed CSF flow.
We also know that drainage of CSF out of the brain is via the pacchionian granulations into the dural sinuses which are drained by the jugular veins. Damadian also found it surprising that CSF drainage was diminished in the erect position. But since we know that, in both MS patients and controls, jugular vein flow is diminished in the upright position while cerebral blood flow is unchanged, one could argue that Damadian and Chu are showing that altered venous outflow of the jugular veins is a significant factor in diminished CSF flow.
Nice first attempt. For your information, group, i reached out to Ray Damadian to evaluate CSF flow before and after treatment of venous obstructions. He was interested in spinal alignment not venous abnormalities at the time.