DrSclafani answers some questions

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Re: DrSclafani answers some questions

Postby drsclafani » Tue Jan 08, 2013 5:48 pm

NZer1 wrote:We all put allot of 'faith' in 'Peer Reviewed Publishings',

Does the Literature say that MS is an Auto-Immune disease?

Does the Literature show how that conclusion is supported?

I like to play the Atheist Advocate and ask who do we trust and why?

Money has decided the conclusion in many situations in Medicine and it has been very difficult to challenge and then correct information when necessary because it takes more money to do so.

Food for thought and direction finding,
Nigel

The eyes will see what the eyes are trained to see and the mind will therefore determine the vision.


Nigel, the system is not perfect and we hear about plagirism and falsified data more frequently than in the past. I think it is the result of, not more unethical behavior, but of more srutiny.

we are living with lots of assumptions and misconceptions that were never analyzed by peer review as we know it now. Reviewers are now completely blinded to the names of the author or the location from which the paper orginated. This is not perfect as we reviewers can recognize writing style, researcher interests, etc. Nonetheless is becomes more and more scrutiny and assumptions are questioned far more than at II.U (the Universty of the Internet)
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Re: DrSclafani answers some questions

Postby pelopidas » Wed Jan 09, 2013 12:31 am

milesap wrote:A good video the cause of MS and CCSVI worth a look
http://www.abc.net.au/catalyst/stories/3572695.htm



"In a healthy individual, a bacteremia (where bacteria get into the blood stream through a minor cut or wound) would normally be cleared quickly with no adverse consequences. If a heart valve is damaged and covered with a piece of blood clot, the valve provides a place for the bacteria to attach themselves and an infection can be established." infective endocarditis , wikipedia

Normal valves and good blood flow won't let bacteria grow
Last edited by pelopidas on Wed Jan 09, 2013 3:32 am, edited 1 time in total.
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Re: DrSclafani answers some questions

Postby NZer1 » Wed Jan 09, 2013 1:44 am

A wee question for you Dr S.

What causes neck veins to go out of shape, expand, balloon often above and below valves or narrowings?
For instance the extremes like Rici's.

Is it the same thing as Leg veins and Varicose Veins where the vein changes shape and enlarges?

Found some interesting thought starters today when I was researching the change in symptoms those of us with CPn go through on the Protocol.

" Monocyte Stickiness and heart disease
Monocytes are large immune cells that eventually turn into macrophages, the garbage collectors of the immune system. Before they turn into macrophages, monocytes drift along in the bloodstream, eating a germ here, a dead cell there, and generally behaving themselves. In the course of their travels they brush against the endothelial cells in our arteries, bounce off, and continue to drift. Occasionally, however, a monocyte will stick to an endothelial cell, then creep into the wall of the artery where it turns into a macrophage and where, sometimes, it becomes a foam cell. When millions of macrophages have become foam cells in one area, we have an atherosclerotic plaque.
Researchers from the University of Wisconsin designed a study to find out why some monocytes, but not others, stick to endothelial cells. They found that monocytes infected with CPN were stickier than uninfected monocytes.
1 Furthermore, the more heavily infected the monocytes were, and the longer they had been infected, the stickier they became. The CPN didn't have to be alive--monocytes that ate dead CPN organisms also became sticky."
http://www.potbellysyndrome.com/attach/CPN.pdf


And, the symptom changes in CPn treatment are often caused by Porphyria (poor-FEAR-ee-uh) refers to a group of disorders that result in a buildup of chemicals called porphyrins in your body.

"Porphyria arises from a disruption in your body's production of a substance called heme.
Heme is found in all of your tissues, but the largest amounts are in your red blood cells, bone marrow and liver. Heme is a major component of hemoglobin, an iron-rich protein that gives your blood its red color. Hemoglobin enables red blood cells to carry oxygen from your lungs to all parts of your body, and to carry carbon dioxide from other parts of your body to your lungs so that it can be released when you exhale.
Eight enzymes convert chemicals called porphyrins into heme. In porphyria, an inherited mutation in one of the genes involved in heme production can cause an enzyme deficiency, which can lead to porphyrins building up in your body. Although porphyrins are normal body chemicals, it's not normal for them to build up."
http://www.mayoclinic.com/health/porphy ... THOD=print


The connection with Bacterial Infections, the die off toxins (endo-toxin) and the diet of a PwMS 'could' easily create a RRMS health issue. Altering the Diet to a more anti bacterial herbal content will influence the disease stats. The bacterial infection can cross the BBB and cause Brain Tissue Lesions, and it can cause Vascular disruption to wall linings and to Valve leaflets. The result can be reflux/back jets which compound the breaching of the BBB and Lesion load on grey and white matter. The Infection robs ATP from the host cells causing Fatigue. Many other symptoms are common between MS and bacterial diseases such as CPn and Lyme and there is a co-incidence of CPn and Lyme and MS.


I have always thought that it is not what you know but what you don't know that is important.

And I have often believed that the answers are out there, the pieces of the puzzle simply haven't been placed as yet.

Deep in thought,
Nigel
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Re: DrSclafani answers some questions

Postby drsclafani » Thu Jan 10, 2013 6:49 am

pelopidas wrote:
milesap wrote:A good video the cause of MS and CCSVI worth a look
http://www.abc.net.au/catalyst/stories/3572695.htm



"In a healthy individual, a bacteremia (where bacteria get into the blood stream through a minor cut or wound) would normally be cleared quickly with no adverse consequences. If a heart valve is damaged and covered with a piece of blood clot, the valve provides a place for the bacteria to attach themselves and an infection can be established." infective endocarditis , wikipedia

Normal valves and good blood flow won't let bacteria grow

P-
sometimes it is an infectious process that causes the damage of a normal valve and this predisposes to further damage. Is not rheumatic fever in a child such an occurrence?

It is interesting to look at the veins of patients with Lymes. The appearance on IVUS and ultrasound nd suggests infectious or inflammatory process of the vein AND the valve that is much different from the vein and valve of PwMS

still initial observations, not anything I am convinced of in lymes yet

s
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Re: DrSclafani answers some questions

Postby dlynn » Thu Jan 10, 2013 8:46 am

Dr. Sclafani
Is inflamation of the veins always an issue for someone who had Lymes in the past?
or do the veins return to their normal state
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Re: DrSclafani answers some questions

Postby Cece » Thu Jan 10, 2013 9:15 am

Cece wrote:Lyme's patient:
drsclafani wrote:Image


MS patient:
drsclafani wrote:Image

For reference since we are on the topic...
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Re: DrSclafani answers some questions

Postby NZer1 » Thu Jan 10, 2013 12:14 pm

dlynn wrote:Dr. Sclafani
Is inflamation of the veins always an issue for someone who had Lymes in the past?
or do the veins return to their normal state


These are the sorts of questions I am interested in.
If for instance I have had CPn for decades then what will my valves look like and will they all be equal in the entire system. Some may be newly infected and others infected for years and inert.

The vein walls are infected by the process of the bacteria entering endothelial cells, is that going to be detectable or is it known to cause issues that can be observed by non invasive technology, for instance will vein walls change shape or deform in a way that can be assessed?

If there is inflammation processes going on does that mean they will be obvious on IVUS or is it only at certain stages that IVUS can detect it.

Is the Doppler assessment able to give any indications of inflammatory diseases.

Have Autopsy Studies looked for bacterial involvement in Arteries and Veins in diseases such as CCSVI or de-generative diseases such as MS?

If the blood testing for Lyme and CPn is very inaccurate then how do we improve knowledge of infective agents in veins and arteries?

Lyme and CPn are two bacterial diseases that have been noticed in Vascularture, there are only 0.04% of all bacteria that are known to Medicine, and there are many trillions in our entire body.

If all the Bacteria could talk to each other who would be in 'control' of our body? The one who can talk loudest?

Have a Happy Day,
Nigel
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Re: DrSclafani answers some questions

Postby Frangoula » Thu Jan 10, 2013 1:05 pm

I had read words Upper Cervical on a post to Dr. Sclafani and happen to have it done in Tyler, TX, by a chiropractor and did notice an improvement in my standing and cooking at my kitchen counter upon coming back home that evening to Shreveport, LA. There was a small noticeable improvement when bending over and standing and cooking at my kitchen counter.
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Re: DrSclafani answers some questions

Postby drsclafani » Thu Jan 10, 2013 10:52 pm

NZer1 wrote:
dlynn wrote:Dr. Sclafani
Is inflamation of the veins always an issue for someone who had Lymes in the past?
or do the veins return to their normal state


These are the sorts of questions I am interested in.
If for instance I have had CPn for decades then what will my valves look like and will they all be equal in the entire system. Some may be newly infected and others infected for years and inert.

The vein walls are infected by the process of the bacteria entering endothelial cells, is that going to be detectable or is it known to cause issues that can be observed by non invasive technology, for instance will vein walls change shape or deform in a way that can be assessed?

If there is inflammation processes going on does that mean they will be obvious on IVUS or is it only at certain stages that IVUS can detect it.

Is the Doppler assessment able to give any indications of inflammatory diseases.

Have Autopsy Studies looked for bacterial involvement in Arteries and Veins in diseases such as CCSVI or de-generative diseases such as MS?

If the blood testing for Lyme and CPn is very inaccurate then how do we improve knowledge of infective agents in veins and arteries?

Lyme and CPn are two bacterial diseases that have been noticed in Vascularture, there are only 0.04% of all bacteria that are known to Medicine, and there are many trillions in our entire body.

If all the Bacteria could talk to each other who would be in 'control' of our body? The one who can talk loudest?

Have a Happy Day,
Nigel

Nigel
thank you for asking so many good questions. it will halp me look for answers.

At the current time I have imaged too few patients with infection to give you emphatic answers. For me, this is just the beginning.

DrS
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Re: DrSclafani answers some questions

Postby drsclafani » Thu Jan 10, 2013 10:53 pm

Frangoula wrote:I had read words Upper Cervical on a post to Dr. Sclafani and happen to have it done in Tyler, TX, by a chiropractor and did notice an improvement in my standing and cooking at my kitchen counter upon coming back home that evening to Shreveport, LA. There was a small noticeable improvement when bending over and standing and cooking at my kitchen counter.


thank you Frangoula

DrS
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Re: DrSclafani answers some questions

Postby pelopidas » Thu Jan 10, 2013 11:56 pm

drsclafani wrote:P-
sometimes it is an infectious process that causes the damage of a normal valve and this predisposes to further damage. Is not rheumatic fever in a child such an occurrence?

It is interesting to look at the veins of patients with Lymes. The appearance on IVUS and ultrasound nd suggests infectious or inflammatory process of the vein AND the valve that is much different from the vein and valve of PwMS

still initial observations, not anything I am convinced of in lymes yet

s


And this explains a lot of symptoms of Lyme disease. Maybe these initial observations are going to change some day everything we know about the way this infection affects central nervous system
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Re: DrSclafani answers some questions

Postby NZer1 » Fri Jan 11, 2013 12:38 pm

My comment to Dr F; post203166.html#p203166
Dr F I am beginning to see evidence that the articles about CSF flow and Vascular flow are secondary to the issues of Bacterial and Viral influence on the structure of tissues not only in veins and sinuses but also the influence in the Vit D VDR dyregulation.

It appears we have a chicken and egg situation that has occurred because of the technology available to support theories as time moves on.

The Vit D influence across many critical systems answers more questions that the basic flows and alignments because it confronts the cause of flows and alignments rather than saying that problems begin at any point, it indicates the multi factual findings of symptom outcomes from the spectrum of treatments we are trying, eg CCSVI PTA, AO adjusting, Diet, Stress minimising, hereditary links, geographical links, endothelial involvement, immune system activation, exercise and many more.

The bacteria and virus involvement is effecting many tissues and systems to support life continuum for itself, it is almost driving us rather than being simply a parasite on us.

The growing awareness that Inflammation is major problem in all diseases and health issues is now redirecting Medical Science's focus to understanding primary Health at a new and deeper level and that the primary causes a cascade leading to secondary diseases.

I don't think there will be a simple one stop fix, I do think that we have to remain open minded and flexible with our reading and thinking so that the pieces are free to fall into place.

It will take 'specialists' to push their barrows so that all points are brought to the table for consideration, respect of others inputs is vital imo.

Nigel

Check in with this thread for more thoughts on Vit D and the VDR dsyregulation.
post203165.html#p203165
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Re: DrSclafani answers some questions

Postby CureOrBust » Fri Jan 11, 2013 4:53 pm

Please, this thread topic is "DrSclafani answers some questions" its NOT about posting your personal thoughts on items slightly related to CCSVI which Dr Sclafani treats. Please show respect to others reading this thread, and start your own thread if you wish to move off topic.
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Re: DrSclafani answers some questions

Postby NZer1 » Fri Jan 11, 2013 5:08 pm

Thanks for stating your personal opinion Cure,

the good thing is Sal and I communicate off TiMS as well and I have worked on items with him before, I believe if there was a problem on his thread he would either publically or in private speak to me.

The purpose of the thread is to look at all aspects of what Sal does and factors that influence the treatment and outcomes, I believe that is what has been occurring here. And the Education befits everyone!

If that is not the case, can you explain your problem with the discussion that is occurring Cure.

Kind Regards,
Nigel

ps I had already started a thread for those who missed it here.
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Re: DrSclafani answers some questions

Postby drsclafani » Sat Jan 12, 2013 12:43 am

NZer1 wrote:Thanks for stating your personal opinion Cure,

the good thing is Sal and I communicate off TiMS as well and I have worked on items with him before, I believe if there was a problem on his thread he would either publically or in private speak to me.

The purpose of the thread is to look at all aspects of what Sal does and factors that influence the treatment and outcomes, I believe that is what has been occurring here. And the Education befits everyone!

If that is not the case, can you explain your problem with the discussion that is occurring Cure.

Kind Regards,
Nigel

ps I had already started a thread for those who missed it here.



cureorbust and nzer1
please see private message

To all others, please express opinions about cureorbust's objection.

regarding nzer1's statement that I would give my opinion about what is written if i didnt like what was written....i am unlikely to do so because i am only a humble plumber who will not herd this thread in any direction.

personally, i would be more fulfilled if there were more questions, especially from newbies who are trying to work their way through the tall grass of ccsvi. Sometimes those who have benefited the most during the years, may be inhibiting those who have much to learn because their knowledge base, much to my satisfaction, is quite sophisticated
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