This Is MS Multiple Sclerosis Community: Knowledge & Support

Welcome to the world's leading forum on Multiple Sclerosis research, support, and knowledge. For over 10 years, This is MS has provided an unbiased community dedicated to Multiple Sclerosis patients, caregivers, and affected loved ones.
It is currently Mon May 20, 2013 10:10 am

View unanswered posts | View active topics


Board index » Treatments » Chronic Cerebrospinal Venous Insufficiency (CCSVI)

All times are UTC - 8 hours [ DST ]



Post new topic Reply to topic  Page 1 of 1
  [ 2 posts ] 
  Print view Previous topic | Next topic 
Author Message
zap
PostPosted: Thu Mar 18, 2010 6:14 am 
Offline
Family Elder
User avatar

Joined: Mon Apr 20, 2009 3:00 pm
Posts: 326
I originally posted this in the "valve regeneration" thread but thought it was kind of off topic and moved it here ... for context I was MRV scanned @ Stanford and found no significant stenoses. Some of had Doppler tests done that reveal faulty of absent valves in the jugulars - now I'm wondering if there may be MS/CCSVI conditions even in patients with no major venous narrowings ...

-----------------------------------

zap wrote:
If the valves in the right JV were missing or compromised (but not blocked), would MRV even show it? I'm wondering if an apparently normal MRV could result when a patient with missing jugular valves is scanned ...

So even in the absence of CCSVI, could transient blood reflux up into the brain cause MS lesions and damage, if valves are not normal?

And here's a sort of out-there question I've harbored for awhile now - could sneezing cause such backjets? I sneeze VIOLENTLY, several times, on most days, and I've often wondered if the spike in thoracic pressure this causes could be an issue ...


In case that sounds wacky, check out these:

Quote:
Internal jugular valves are the only venous valves between the heart and the brain. Conditions such as coughing and other precipitating activities may result in retrograde cerebral venous flow because of the absence or presence of internal jugular valve incompetence, allowing brief transmission of high venous pressure and resulting in brain disturbance.


http://www.jultrasoundmed.org/cgi/reprint/21/7/747.pdf

Quote:
The pathophysiology of primary exertional headache (EH) is unknown. Physical exertion is associated with Valsalva-like manoeuvres (VM). VM leads to increased intrathoracic pressure and reduces cerebral venous drainage. Internal jugular vein valve incompetence (IJVVI) leads to retrograde venous flow during VM with transient increase of intracranial pressure


http://www3.interscience.wiley.com/jour ... 6/abstract


I know that this issue has been discussed before, regarding Transient Global Amnesia - and been sort of dismissed, since "CCSVI is chronic" and the TGA patients' "valsalva-like" spikes aren't chronic, they are transient damage ... but I think there is plenty of grey area between, and Schelling's work seems to support this.

Repeated minor spikes over time is chronic - who says the reflux must be constant and unwavering to cause MS like lesions and symptoms?

There is also a continuum of thoracic pressures - for example, perhaps poor sitting posture, sleeping position, etc and/or unusual physiology causes an increased thoracic pressure in the absence of venous stenoses. This would not show up in MRV (apparently valve incompetence requires special doppler tests), but could still result in CCSVI - perhaps more mild than those with seriously blocked jugulars, but serious nonetheless!

Related threads:

http://www.thisisms.com/ftopic-9863-day ... ar-15.html
http://www.thisisms.com/ftopicp-53518.html#53518
http://www.thisisms.com/ftopict-9698.html
Top
 Profile  
 
Salvatore24
PostPosted: Thu Mar 18, 2010 7:05 am 
Offline
Family Elder
User avatar

Joined: Sun Nov 29, 2009 4:00 pm
Posts: 109
Location: Melbourne, Australia
zap wrote:
Quote:
Internal jugular valves are the only venous valves between the heart and the brain. Conditions such as coughing and other precipitating activities may result in retrograde cerebral venous flow because of the absence or presence of internal jugular valve incompetence, allowing brief transmission of high venous pressure and resulting in brain disturbance.


Hmm, interesting about the coughing link. I had a pretty bad case of whooping cough when I was 16-17, so bad that at times I couldn't breathe for 5-10 seconds. The plot thickens.....
Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  Page 1 of 1
  [ 2 posts ] 

Board index » Treatments » Chronic Cerebrospinal Venous Insufficiency (CCSVI)

All times are UTC - 8 hours [ DST ]

Related topics
 Topics   Author   Replies   Views   Last post 
There are no new unread posts for this topic. Valves vs stenoses

greyman

10

1836

Sat Jan 30, 2010 1:24 pm

Zeureka View the latest post

There are no new unread posts for this topic. Faulty valves jugular

newveins

2

917

Wed Oct 20, 2010 9:36 pm

newveins View the latest post

There are no new unread posts for this topic. Internal jugular vein valves in healthy subjects

Cece

1

731

Sat May 14, 2011 5:22 pm

1eye View the latest post

There are no new unread posts for this topic. CCSVI Evolved and the Missing Infectious Link

vesta

3

179

Sun May 19, 2013 4:57 pm

lena-g View the latest post

There are no new unread posts for this topic. Ultimate CCSVI treatment for defective valves of IJV

Nunzio

5

1516

Wed Aug 31, 2011 12:15 pm

civickiller View the latest post

 


Who is online

Users browsing this forum: No registered users

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum

Search for:
Jump to: