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I also find it interesting that groups of these oligodendrocytes also group up in the white matter of the brain around veins.....just like MS lesions.
Billmeik wrote:are you sure that ism't dead oligos that are around lesion veins. Hypoxia is killing them, causing the inflammation that causes the ms.
Just a theory.
MarkW wrote:Hello Johnnymac,
Looks like you have outlined about 10+ years of research before we get any definitive answers. I suspect that the key to this research will be replacing the current mouse model of MS with a dog/pig model which includes CCSVI. Interesting thoughts, just do not hold your breath, waiting for an answer.
Dunno. In that thread me and cheerleader agreeed it was oxygen.
Billmeik wrote:but the apoptosis isnt needed if the cell death is caused by hypoxia. I've been a believer in tha apoptosis of oligos in ms for almost 10 years. Now I don't see why cellular suicide is needed. Hypoxia.
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