I believe that the restenosis that the patient notices is some of the key here
The patient does not feel the restenosis. Only can feel its effects. That's why it can be used as control
It indicates that placebo doesn't currently exist and retesting will support that.
Do you refer to the placebo effect or to the possible placebo group in a trial? Placebo effect exists and always has to be considered.
This is also proof that the treatment works if the patient knows they have regressed.
If the changes that treatment made can be measured then you have a tool for overcoming the placebo debate.
If we count restenosis vs. non-restenosis among the people that regressed we will have prove that wrong venous flow affects health among MS patients.
Now taking the opposite angle, could the symptoms be recreated in another patient who is CCSVI free. That is to say to recreate the same style/type of stenosis that on the treatment table created immediate improvements for a CCSVI treated patient.
This may open a nest of possibilities and provide some insights. It most likely will show the variety of outcome that the blocked veins can create and the effects of time will be even more interesting.
Are you proposing to create artificial MS in patients? Obviously is completely unethical. About creating MS in animals is a problem because we are the only two-legs mammal, and we have a special neck area. This will probably will make difficult to reproduce the effect in other animals. Besides animals cannot tell you how they feel and the lesion presence that could be found in them is not the whole story about CCSVI.