This Is MS Multiple Sclerosis Community: Knowledge & Support

Because of their anastomotic interconnections, only simultaneous obstruction of veins of Galen and basal veins wil effectively obstruct deep venous outflow. This can occur in the tentorial incisura, from swelling or displacement of the midbrain due to brain oedema, haematoma or tumour. Complete obstruction of great vein of Galen and basal veins leads to rapid death. In patients who survive incomplete obstruction, various combinations of damage to parts of the deep venous territory exist. This is possible because very many tributaries of the deep system unite below and sometimes above the tentorial incisura. The hallmarks these varying deep venous obstructions have in common are sparing of the subcortical white matter of the convexity, and cortical involvement limited to the limbic lobe and visual cortex. Obstruction of cerebral venous outflow explains many pathological phenomena. Treatment must aim at relieving this obstacle to blood flow.