check out the thread "Phlebotomy anyone.." for much more about iron
I started following the thread, with some skepticism, and gradually started to see the sense of it--got iron panels done a number of times, seemed to indicate a problem, so got genetic testing--and am heterozygous for the H63D mutation of Hemachromatosis (iron overloading disease).
Had one phlebotomy, and felt amazingly better. Will donate blood once again on the first day they will let me (56 day wait between donations).
But is important to check your bloods about a month after the phlebotomy--you need to check your iron panel (total iron, TIBinding Capacity, transferrin saturation, and ferritin), and a CBC for the RBC, WBC, hemoglobin and hematocrit. When you donate, the CBC bloods go down, and thru the month as new bloodo cells are being made to replace those you donated, the Total iron,Trans sat and ferritin levels come down--that is, you are using storage iron to make the new cells. So if you have hemachromatosis, you are getting the results you want--a lowering of storage iron.
But if you don't have a prob with high iron storage, you could go too low with repeated blood donations.
The mechanism for iron in the brain is not fully known, but does not
seem to hinge on excess iron according to info so far--you could be storing iron in brain even if your total iron stores are low.
Yet, the blood donation of a pint gave me energy I have not had for years (is waning as the time goes by--been a bit over a month--but still is a more even energy than before). And as I say, I will donate again, and see if get same great response.
Still doing research to see why got immediate reaction--since immediately after the blood donation, your WBC, RBC, Hematocrit and hemoglobin all go down (the blood panel takes a few weeks to start going down)--and you would think you would have less energy, not more.
EDTA drips might be helpful to get rid of iron in brain.
From what I have read, IP6 will not do it, despite some claiming it does.