This Is MS Multiple Sclerosis Community: Knowledge & Support

hi Cece .. i'm thinking about those that lift so heavy it looks as if their neck is going to burst. Not to say that's not you.

. i'm thinking about those that lift so heavy it looks as if their neck is going to burst.

hi sbr487.. i would very much like to have a look..only 'shared' once myself and now can't remember how I did it. Something to do with parking it to another website..
Are the recommendations pre or post ccsvi theory?

Cerebral blood flow during exercise: mechanisms of regulation
Shigehiko Ogoh1 and Philip N. Ainslie2
1Department of Biomedical Engineering, Toyo University, Kawagoe-shi, Saitama, Japan; ; 2Department of Human Kinetics, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, British Columbia, Canada

Submitted 27 May 2009 ; accepted in final form 1 September 2009

The response of cerebral vasculature to exercise is different from other peripheral vasculature; it has a small vascular bed and is strongly regulated by cerebral autoregulation and the partial pressure of arterial carbon dioxide (PaCO2). In contrast to other organs, the traditional thinking is that total cerebral blood flow (CBF) remains relatively constant and is largely unaffected by a variety of conditions, including those imposed during exercise. Recent research, however, indicates that cerebral neuronal activity and metabolism drive an increase in CBF during exercise. Increases in exercise intensity up to 60% of maximal oxygen uptake produce elevations in CBF, after which CBF decreases toward baseline values because of lower PaCO2 via hyperventilation-induced cerebral vasoconstriction. This finding indicates that, during heavy exercise, CBF decreases despite the cerebral metabolic demand. In contrast, this reduced CBF during heavy exercise lowers cerebral oxygenation and therefore may act as an independent influence on central fatigue. In this review, we highlight methodological considerations relevant for the assessment of CBF and then summarize the integrative mechanisms underlying the regulation of CBF at rest and during exercise. In addition, we examine how CBF regulation during exercise is altered by exercise training, hypoxia, and aging and suggest avenues for future research.