This Is MS Multiple Sclerosis Community: Knowledge & Support

I have the worst neurological pain in my legs, burning, burning! How could that be caused, related to blocked veins, anyone?

I'm sorry you have such pain. I had a friend's mom with MS, who had this, it was hard on her.

How could it be related to blocked veins. If your azygous is blocked, the reflux has weakened the wall lining and leaked blood and t-cells and whatnot into the spinal cord. Deoxygenation of the nerves of the spinal cord may have occurred because slow removal of deoxygenated blood has prevented fresh oxygenated blood from coming in. Some of these nerves have died and the immune system comes in to clean it up and makes the damage bigger in the process. This creates a lesion in the spinal cord and the nerve damage creates a sensation of burning in the feet? Not exactly sure how the last bit works but it's however the phenomenon would've been explained by the autoimmune theory. But with luck some of the area of the spinal cord near the lesion is only compromised (because of lack of blood flow) and not dead, so when proper blood flow is restored, that area of the spinal cord is no longer compromised and regains proper functioning and the neurological pain might be reduced or, again with luck, gone.

Until someone comes along with a better explanation....

ThornyRose,
I cannot explain how when some areas of the brain are affected by MS inflammation, the result is leg pain, arm pain, back pain, or whatever. The brain is a very complex thing, as we all know.
I know that I had about 30 bottles of pills by my bed for all of my pains, spasms, cramps, etc. etc. etc. etc. etc. etc.etc. etc.etc.

Now that I have been liberated, I take only one baby aspirin /day.
No more pain. ANYWHERE.
One of my first and last symtoms was as if an iron was burning into my right thigh top. I used to dream someone was ironing clothes on my legs.
Please believe me. No more pain.
I know my brain loves the blood flow.

Sincerely, Rose2

Actually, Cece, as much as I admire all your knowledge and input, I have to disagee with you here. I absolutely do not believe the autoimmune theory anymore as the fundamental cause of MS (although there is some inflammation/immune activity going on). However, if the cause of nerolological pain is dead or injured brain or spinal tissue, then however it is killed or injured would result in pain. This would include if the tissue were killed or injured by autoimmunity.

Disagreeing is good, as is flattery. What I meant it pretty much what you said. At that point the immune system does the clean-up and further damage, just as in the autoimmune theory that is when the immune system does clean-up and damage. The difference is what activates the immune system: a never-found autoimmune MS antigen (nope) or dead & dying hypoxic iron-laden nerve cells (yes).

I no longer believe there is an ounce of autoimmunity in MS either.