Good morning Selkie,
Prokarin - combines histamine and caffeine. Both are known vasodilators (open the blood vessels).
I'm not familiar with Prokarin but I thought that caffeine was a vasoconstrictor?
I replied to this message earlier in the day but somewhere along the way it got lost.
There are some misconceptions about Prokarin when it comes to the role of caffeine. When Prokarin metabolizes in the body, H2 neuroreceptors are produced and these improve the conductivity of nerve impulses which effect several other physiological functions in your system.
The caffeine in Prokarin is used to slow down and regulate the histamine breakdown. Otherwise it would be out of your system in less than an hour. The amount of caffeine in a daily dosage of Prokarin would be the same as sipping on one cup of coffee over a 16 hour period, hardly enough to effect the average person in any way at all.
Unfortunately some MS docs have stated that it is the caffeine in Prokarin that helps reduce some of a patient's MS symptoms. These docs have made these comments from a position of ignorance which is truly sad. Probably the same docs who are trashing CCSVI as well!
The H1 histamine receptors are another matter and may not be good for people contemplating CCSVI. H1 receptors are not produced by Prokarin.
If anyone wants to read more about the theory of why Prokarin has helped reduce the symptoms in MS patients, you can go to www.edmsllc.com
and learn more about it.