Viagra for CCSVI?

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Viagra for CCSVI?

Postby syckbastid » Thu Sep 09, 2010 6:35 am

I'm not being facetious... Since Viagra (and drugs like it) increase blood flow, couldn't it be benenficial in treating CCSVI? Thoughts?
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Postby Billmeik » Thu Sep 09, 2010 7:20 am

it is a vasodilator.
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Postby Rokkit » Thu Sep 09, 2010 8:19 am

It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D
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re

Postby jean-la-grenouille » Thu Sep 09, 2010 9:34 am

I took Cialis from time time (another drug similar to Viagra) and had noticed I felt better the day after (better balance and less sensitivity troubles)...
(Be careful with self medication using these drugs...)
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Postby patientx » Thu Sep 09, 2010 10:17 am

Rokkit wrote:It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D


Someone has:
http://www.clinicaltrials.gov/ct2/show/ ... gra&rank=1

Please note: this does not mean everyone should run out and start taking Viagra.
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Postby CaptBoo » Thu Sep 09, 2010 10:26 am

That was proposed in 2004. I wonder if the study actually took place.

Also note that participants are excluded if they have a vascular disease. According to Zamboni that would rule out anyone diagnosed with MS.

Now I see that it has been completed, but the study was not published.
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Postby 1eye » Thu Sep 09, 2010 10:36 am

I think it was explained by Dr. Sclafani that those chemicals work only on very small vessels, not jugular or VV size even.

Seriously, the best such solution for CCSVI and ED sufferers who can, besides Liberation, is to stop taking Effexor. Or other ssri's.
"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'MS' is over - if you want it
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Postby cheerleader » Thu Sep 09, 2010 10:49 am

patientx wrote:
Rokkit wrote:It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D


Someone has:
http://www.clinicaltrials.gov/ct2/show/ ... gra&rank=1

Please note: this does not mean everyone should run out and start taking Viagra.


Thanks for finding this patient. I find it ironic that the NIH will study hypoperfusion in relation to a drug, but will not study it in relation to a vascular condition. Note the papers the NIH links to as rationale (Lassmann et al) The same papers I've been linking to re: slowed blood flow in MS brains. This quote is a kick:
Although people with MS can have reduced blood flow in the brain as part of the disease process, it has been observed that men with MS may have increased blood flow to the brain while taking sildenafil citrate. This study will measure brain blood flow or blood volume in men and women with MS before and after taking Viagra and compare the results to those in healthy volunteers in an effort to better understand the disease.

Why not try and learn how come pwMS have reduced blood flow to the brain?? Why is it always about a pill?

PS--natural ways to get the same vasodilation are niacin flushes, sunshine, cardiovascular exercise, proteolytic enzymes all in the endothelial health program, now on www.ccsvi.org under "helping myself"

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Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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Postby patientx » Thu Sep 09, 2010 12:08 pm

Why not try and learn how come pwMS have reduced blood flow to the brain??

This is just one study done by the NIH. They and others have studied reduced CBF, but it's not a simple thing to figure out.

Why is it always about a pill?

PS--natural ways to get the same vasodilation are niacin flushes,

Doesn't niacin come in pill form?
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Postby cheerleader » Thu Sep 09, 2010 12:51 pm

patientx wrote:Doesn't niacin come in pill form?


Viagra (TM)= about 10 bucks for the little blue pill.
Niacin (no trademark)= about .03 for a little pill
link to blue pill
http://www.vitacost.com:80/Natures-Way- ... iacinamide

The reason I made my flippant pill joke, patient, is because our TIMS friend Marc has spoken with NIH regarding CCSVI studies, and they were not interested. I just find it odd that the NIH isn't interested into looking at a possible mechanism for slowed perfusion, but will study the effects of viagra. I'm assuming the results weren't impressive, since they never released them.
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http://ccsviinms.blogspot.com
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Postby joge » Thu Sep 09, 2010 1:14 pm

I'm ready, I'm ready !
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Postby scorpion » Thu Sep 09, 2010 3:49 pm

Rokkit wrote:It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D


I do not think it would work either Rokkit but hey if it is does I stand erected.
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Postby Lyon » Thu Sep 09, 2010 3:53 pm

.
Last edited by Lyon on Sun Nov 20, 2011 6:25 pm, edited 1 time in total.
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Postby HappyPoet » Thu Sep 09, 2010 3:59 pm

scorpion wrote:
Rokkit wrote:It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D


I do not think it would work either Rokkit but hey if it is does I stand erected.

LOL, scorpion, this is so funny! I can't stop laughing. Really!
Good one. :lol:
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Postby scorpion » Thu Sep 09, 2010 4:13 pm

HappyPoet wrote:
scorpion wrote:
Rokkit wrote:It's a nice thought, but given that ED affects up to 80% of men with MS I would think someone would have noticed a correlation by now. I guess we could give it to the women and see if it helps them. :D


I do not think it would work either Rokkit but hey if it is does I stand erected.

LOL, scorpion, this is so funny! I can't stop laughing. Really!
Good one. :lol:


Thanks HappyPoet. I try hard to be the forum clown on Thisisms but you know the competition is stiff! :wink:
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