1. 100%, 100%, 100%
2.no blind study to test against placebo effect
Dr. Sclafani has addressed this in his thread. He believes that it is unethical to sedate people to the extent that would be necessary such that they could not tell whether or not they were actually treated. Many people treated for CCSVI have reported that it was obvious when the balloon was being inflated. Sedation would expose people to unnecessary risk. Moreover, simply inserting a catheter into the jugular or azygous vein may clear out some obstruction. There are many types of blockages including a septum, a thin membrane blocking the vein, which could be cleared via a catheter insertion. Moreover, Zamboni's paper states that the doctors evaluating the patients were blinded to an individuals MS status.
3.participants in his study continued to take MS therapy drugs
Pharmaceutical companies do this all the time. Remember Avonex + Tysabri? Copaxone with Revimmune? Copaxone with Novantrone? Anyways, MS/CCSVI may be a disease of chronic immune activation and continuation of DMDs may be prudent to help correct the chronically activated immune system.
4. he went straight to the social media which bypassed any critical review of his research by his peers
False. Zamboni published in peer reviewed science journals well before the rest of us found out about it.
5.to perform the "liberation" procedure at such an early stage in his research was a questionable ethical decision
Really? How else would you suggest he test his hypothesis that restricted blood flow may be a contributing factor to the disease of MS?
6. to operate on his wife was a questionable ethical decision
This has been discussed elsewhere on the forums here at ThisIsMS. Zamboni did not operate on his own wife. Moreover, it may be the case that it's unlikely that he's personally operated on anyone recently. Have you watched the videos of his interviews? If you were paying attention, then you would have noticed something unusual about his hands. In one video he handles a computer mouse as though he were wearing a ski mitten. In another, he moves his hand over to rest it down on his other arm and it appears to be more of a flop type of motion. If you've read about Zamboni, then you may have discovered that he has an unknown (at least to me) neurological condition. Clearly, this seems to be affecting his hands (or at least one of them). Again, I doubt that he operated on his own wife. However, he may have directed the operation. I see no ethical problems with this if that were the case.
7.the word "liberation" should never have been used to describe his surgery. liberation means to be free of. what a misleading term.
The use of the word liberation by Zamboni is meant that his procedure liberates the blood flow. As far as I know, it has nothing to do with "liberating people from MS." I believe that this is common misunderstanding. Even Dr. Andrews, an IR in support of CCSVI treatment and research, makes this error in his video.