Given your explanations quoted below, do you believe that most spinal cord MS lesions are due to CSF circulation problems? (and not vein/valve stenoses)?
Is it possible for restenosis of the jugular veins after angioplasty to be caused by CSF pressure?
Is it possible to have CSF problems in the spine as well as vein stenosis valve problems in the veins draining the brain, (that is to say 2 separate problems?)
Who is best equipped to study and treat the CSF problems? Chiropractors in the US? What specialty? Do Osteopaths treat this in the US as well?
In France Osteopaths perform body structure and CSF problems (more or less), but they don’t use x-rays. Also, the French find American Chiropractic to be “very violent” which scares people off.
(there are American chiropractors in Paris) Are American Osteopaths equipped and capable to deal with these problems? Or maybe I should simply ask:
What should MS patients do to study the issue and find treatment? To whom should they address themselves? What should they ask for? (Doubtless the issue is very complicated, but you have to start somewhere.)
(Here is an example of good Osteopathic treatment as performed in France/Recently I was treated by an outstanding Osteopath. He is the official Osteopath for a championship French sports team and is accustomed to putting dislocated muscles and bones back into place. When I arrived I could barely walk and wondered if my nervous system was failing me. No, upon leaving my legs moved freely. And think of it this way. The muscles were so tightly compressed around my pelvic region that they literally prevented my legs from moving. Like a horror film, I could imagine my entire musculature shrinking, compressing my skeleton to the point I was becoming immobilized. He said there was so much tension built into the shoulder/neck/head area that the muscles were compressing all circulation from the head like a vise. So if I think of what these muscles are doing to fluid circulation through my neck, head, and spine I can well imagine a blood reflux injury to the central nervous system - a good definition of MS?)
“Upright doc june 25 2013
I understand Dr. Scalfani's point as to why he prefers angio and IVUS for determing venous flow problems due to stenosis and faulty valves. Angio and IVUS are certainly much better at assesing those types of stenosis and blood flow problems. On the other hand, angio and IVUS are not the preferred method of diagnosing stenosis of the spine and obstruction to CSF flow as a result of increased venous pressure in the VVP due to spondylosis, stenosis and scoliosis of the spinal canal. Spondylosis, stenosis and scoliosis affect the design of the canal, which affects hydrodynamics and CSF flow in the cranial vault and spinal canal. The faulty hydrodynamics get worse during upright posture. X-rays and upright MRI are much better than angio or IVUS for determining these problems.
The other point is that angio and IVUS don't rule out potential structural causes of obstruction to venous flow into the VVP during upright posture. Venous blood preferentially drains into the VVP during upright posture, not the IJs. The upper cervical canal is a key point of obstruction. Angiograms also expose patinets to much more radiation than basic x-rays of the spine and MRI so it makes more sense to get them first to rule out and fix potential structural problems first, espeically if they obviate the need for further more invasive intervention. Treating underlying structural problems may also help improve the durability of venoplasty and stents when necessary. Certain structural problems may also help surgeons better choose between venoplasty versus shunts, such as in a case like CurIous associated with cervical kyphosis and deformation by the transverse process of atlas. I further suspect that venous insufficiency in the azygous and iliac veins can similarly be caused by structural issues sucha as spondylosis, stenosis and scoliosis of the lower spine due to their impact on myofascial tunnels and pressure gradients.
June 25 9:28 am
Structural issues in the spine that affect blood and CSF flow in the cranial vault and spinal canal are far more common and likely a cause of MS, as well as other neurodegenerative diseases than problems in the jugular veins or TMJ for that matter. It makes sense that lesions are often found in the area of spondylosis, bone spurs and stenosis. Spondylosis, stenosis and scoliosis alter the design of the tunnel of the spinal canal. When you change the dimensions and design of a tunnel or pipe you alter the flow of fluids through it. It's basic physics. Although he is a leading expert geotechical engineer and thinks in terms of stone and soil stability so much so that it takes time to sink in like water passing through thick clay, even, my tunneling expert brother gets it. I just have to speak slowly and repeat myself many times. He's been digging around NZ lately Nigel so you better stock up on some caulk and keep an eye out for sink holes.
The VVP is the Vertebral Venous Plexus. Upright posture increases blood flow in and out of the brain which required modifications to the basic drainage system used by mammals. During upright posture, the human brain primarily switches over to the occipital marginal sinus, emissary and accessory venous system that drains into the VVP inside the spinal canal and around the spine. The accessory veins and outlets are the lowest drainage points in the posterior fossa.
Vesta, June 26, 2013
I think that violent venous and CSF backjets due to trauma such as whiplash as proposed by Dr. Schelling is a possible cause of the supratentorial, periventricular and perivenular lesions seen in MS. Chronic ischemia, edema and increased CSF volume due to poor drainage are other causes. Lesions can also be caused by autoimmune-inflammatory conditions and infections.
June 29, 2013
There are many causes of neurodegenerative conditions that are only indirectly related to inflammation. Strokes and ischemic primarily cause damage are due to lack of blood flow. Inflammation is a byproduct of the problem. Hydrocephalus and edema cause compression and stretch neuropathies. Chiari malformations, stenosis, disc herniations etc also cause compression neuropathies. Ligament laxity and joint instabilities, called listhesis, cause stretch neuropathies. Inflammation is a process not a disease. It causes problems when it gets out of control. There are many causes of inflammation. Infection is just one. Burns, scrapes and bruises cause inflammation. Chronic ischemia causes inflammation such as myofascitis in muscles and connective tissues. Atopy and allergies likewise cause histamine reactions and inflammation as part of an over-reactive defense mechanism. For the most part, inflammation is a byproduct of most neurodegenerative conditions, not the cause of it.”