The comment below from my website is an interesting case of MS that involves significant spondylosis (degeneration) and stenosis (narrowing of the spinal canal and intervertebral foramen) of the cervical spine:
Dr. Flanagan I just purchased your book after checking out your site that was given to me on a MS World.
My doctors (PCP and Neuro) both told me I am a weird case patient, gave me some drugs & have pretty much given up on me. I was a perfectly healthy, extremely energetic & vibrant 51 yr old female until Aug 2011.
First symptom (sx) was the immediate onset of floaters in the right eye. Two days later I lost periphrial vision & words became hit & miss. I; have issues with color contrast & depth perception. The left eye is unaffected. After immediate brain MRI, there were no lesions but I was diagnosed with Optic Neuritis. Further testing was done for MS and it's mimics. All of the tests were negative.
At the same time, I developed bilateral severe Restless Leg Syndrome, cog fog, MS hug, sensitivity to light touch and noise, extreme fatigue, and heat intolerance that has progressively gotten worse. I was prescribed meds for that. They are not working anymore. Reason for thought for MS.
Between 2011-2014. Neuro wanted brain MRI's one every year for next five years. I have had three already. They still show no lesions. I am rechecked periodicly for all the MS mimics. Those tests are still all negative. They tell me I'm weird.
Ongoing symptoms - Dizziness when head is tilted back, pressure behind both eyes when overheated, heat intolerance even at the slightest rise in body temp., worse when attacked by a virus, sinus issues (never had them before) loss of balance to the left at times, RLS everynight, loss of bilateral hand strength, left leg weakness. I walk to the left side at times as if i am drunk.
Since 1999 though I have had spinal issues. The diagnosis based on x-rays are degenerative disc disease and degenerative joint diseases of the C4 and C5 & L4, L5, S1 that were corrected with chiropractic adjustments.
In light of recent symptoms, my PCP ordered new MRI's with contrast.
Fast forward to March 2014.
MRI's now show
Cervical: C2-C3 no problems, C3-C4 disc height preserved, disc bulge w/mild bilateral uncovertebral arthropathy, C4-C5 disc height preserved, disc bulge w/bilateral uncovertebral arthropathy. There is narrowing of the anterior CSF space & compression of the ventral thecal sac. There is no central canal stenosis. Facet arthropathy contributes to bilateral foraminal stenosis, moderate on left/mild on right. C5-C6 moderate loss of intervertebral disc space, large posterior disc osteophyte complex which effaces the anterior CSF space and compresses the ventral thecal sac. There is flattening of the ventral cord. There is no central canal stenosis. Facet arthropathy contributes to bilateral foraminal stenosis, moderate to severe on right, mild on left. C6-C7 moderate loss of intervertebral disc height, A large posterior disc osteophyte complex effaces the anterior CSF space and compresses the ventral thecal sac. There is flattening of the ventral cord. There is mild central canal stenosis. There is moderate left sided and mild right sided foraminal stenosis. C7-T1 is fine.
I feel my health issues are cervical related. I don't think I have the start of MS. Going to the chiropractor is not helping anymore since I have to go almost every week. He did start me on some decompression therapy to see if it would help. Two weeks after the therapy, I am back at square one.
Your opinion would be most greatful as I my life is slowly deteriorating at a fast rate it seems. Too young for this. Thank you for your time and I am looking forward in reading your book.