This Is MS Multiple Sclerosis Community: Knowledge & Support

Although serious hepatic toxicity from niacin administration has been reported, it is largely confined to the use of slow-release formulations given as unregulated nutritional supplements.

Abstract
High-dose niacin has versatile and substantial efficacy for the treatment of hyperlipidemias, but its utility is compromised by various side effects, the most serious of which is liver damage. It is proposed that this hepatotoxicity reflects the high demand for methyl groups imposed by niacin catabolism, leading to a reduction in hepatic levels of S-adenosylmethionine (SAM). Depletion of the hepatic SAM pool has likewise been shown to mediate, at least in part, the hepatotoxic effects of ethanol, methotrexate, and niacinamide. If niacin does indeed decrease SAM, a likely consequence would be a counterproductive elevation of plasma homocysteine. Conceivably, methyl group deficiency, by altering membrane properties of skeletal muscle, also contributes to niacin-induced insulin resistance. Concurrent betaine supplementation – preferably administered as a complex with equimolar amounts of niacin – may represent the most cost-effective way to prevent niacin-mediated depletion of SAM and thus avoid hepatotoxicity (and possibly other adverse effects) while controlling homocysteine. Betaine also merits evaluation as an adjuvant to methotrexate and niacinamide therapies.

I have just ordered Gingko capsules but I want to know if people are aware of any serious side effects.

I take 500mg Niacin daily on an empty stomach with Vit C (could be any acid) to produce a strong flush.

For about 20 min a day (while the flush lasts) I feel almost normal. I think I can even pretend to run during that time (normally walk with a cane).

Do not see effects past that though.

Sorry forum I think Ill up the Ginko for the brain help here is another question from me what is a flush ??

I have taken krill oil (thins blood) before the procedure and still do. I have recently added nattokinase after hearing Irishbear76's video on youtube. I am post procedure 3mos and improving weekly.

Ps DONT FORGET THE VITAMIN D!

Off the back of reading this topic, I bought some 100mg Niacin and took some for the first time today with 500mg of Vit C.
HOLY MOLEY!! Now I see what you mean by 'Flush'. It was like having 'Deep Heat Rub' injected into my veins. My whole body turned pink!

Hats off to those people taking 500mg. Sheesh!