@newly: you're right you'd need to be watchful taking plavix and high amounts of fish oil as they are both anticoagulants so you would not want to overdo things.
if i were in your situation i'd be tempted to ensure my fatty acid levels were optimal, carefully monitoring thrombin time etc, and adjust the plavix dosage accordingly.
kiki, histamines do help increase fatty acid levels in the blood, so that hangs together
however, you're not supposed to flush when using niacinamide. interesting that you did depending on histamine intake.
straight, unmodified niacin users are going for the flush intentionally for a variety of benefits. niacin needs to be used with caution though. too much of a good thing and all
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com