The opening challenge from neurologists on Zamboni's theory was that it was unsafe. I suggest that vascular surgeons and IR doing balloon venoplasty across the globe write a joint letter (lead author Prof Zamboni ?) after they reach 5000 patients saying:
'in our research and clinics we have we have treated over 5000 people with Multiple Sclerosis using balloon venoplasty. We have found the procedure we used to be safe. The number of serious problems we encountered was X or x/5 per 1000. We suggest that treating this symptom in pwMS a reasonable decision while further research is conducted. Further publications regarding methodology will follow in specialist journals.'
This type of letter is generally accepted very quickly in medical jourmals which publish weekly. This used to be an important method to share information. Nowadays, journals publish on line immediately and in print later but I suggest using a major global medical journal for such a letter.
The difference between the 2000 pwMS I quoted and 3000 from Cheer is easy to explain. My 2000 figure comes from a web interview with Dr Hubbard which may be viewed on the web:
Cheer's 3000 number was personal information from Prof Dake MD, so you have to decide if you trust it or not. I trust it and hope it will be available in a quotable form before too long.
I am amazed the venoplasty is moving so quickly and hope we pass the 5000 pwMS by balloon venoplasty, in 2011.
MS neuros say more evidence is needed. Double blind, placebo controlled, multi-centre trials are a pre-requisite. Such a trial is not possible to design as a definite diagnosis requires selective venography. The act of selective venography may open webs or sceptums in a stenosed azygos vein, thus giving unintentional treatment at diagnosis !!
De-stenosis is not a cure for MS but I for one have no doubt this symptomatic therapy is worth a try, if like me your MS is progressive.
Mark Walker - Oxfordshire, England. Retired Pharmacist. 12 years of study around MS.
Mark's CCSVI Report 7-Mar-11: