Cavo-spinal phlebography in myelopathies. Stenoses of intern

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Cavo-spinal phlebography in myelopathies. Stenoses of intern

Postby sbr487 » Wed Nov 10, 2010 8:24 am

Only abstract available ...

http://www.ncbi.nlm.nih.gov/pubmed/207127

Increased intraspinal venous pressure, resulting according to ABOULKER in numerous spastic paraplegias and quadriplegias is due to multiple venous abnormalities demonstrated by cavo-spinal phlebography. The most frequent are stenoses of the internal jugular veins, the left renal, the left iliac veins, the azygos veins and compressions of the innominate venous trunks. These abnormalities cause a permanent stasis in the intraspinal plexuses through excessive supply or insufficient drainage. Out of 80 patients, 60 per cent had at least 2 abnormalities, 38 per cent at least 3 abnormalities.
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Postby TMrox » Wed Nov 10, 2010 8:31 am

excellent finding!

Zamboni quotes this article:

"..regarding the causative role of CCSVI in MS, our review of the literature revealed descriptions of associations between the extracranial venous obstructive malformations described herein and disabling neurological pictures however, the latter were defined by these authors generically as myelopathies, without a precise diagnosis and any mention of MS"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647682/
Diagnosed with Transverse Myelitis in December 2008. Inflammatory demyelination of the spinal cord (c3-c5). No MS, but still CCSVI.
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Postby SaintLouis » Wed Nov 10, 2010 8:51 am

What exactly is cavo-spinal phlebography?
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Postby Nunzio » Wed Nov 10, 2010 9:03 am

This is very interesting considering it was done 34 years ago.
I already posted on Dr. Sclafani tread on Oct 27.
Nunzio wrote:
drsclafani wrote:
Nunzio wrote:
drsclafani wrote:.



I also found a very interesting paper from 1976 that is very similar in finding to what Dr. Zamboni/Galeotti do:
Cavo-spinal phlebography in myelopathies. Stenoses of internal jugular and azygos veins, venous compressions and thromboses.

Acta Radiol Suppl. 1976;347:415-7.
Leriche H, Aubin ML, Aboulker J.
Abstract

Increased intraspinal venous pressure, resulting according to ABOULKER in numerous spastic paraplegias and quadriplegias is due to multiple venous abnormalities demonstrated by cavo-spinal phlebography. The most frequent are stenoses of the internal jugular veins, the left renal, the left iliac veins, the azygos veins and compressions of the innominate venous trunks. These abnormalities cause a permanent stasis in the intraspinal plexuses through excessive supply or insufficient drainage. Out of 80 patients, 60 per cent had at least 2 abnormalities, 38 per cent at least 3 abnormalities.

Also is interesting to know that the same group performed surgery on some of those patient with good results.
Acta Radiol Suppl. 1976;347:395-401.
[Intraspinal venous hypertension due to multiple anomalies in the caval system. A major cause of myelopathies]
Aboulker J, Aubin ML, Leriche H, Guiraudon G, Ancri D, Metzger J.
Increased venous intraspinal pressure is described as a venous system disease, resulting in numerous unexplained paraplegias and tetraplegias. The chronic venous stasis in the intraspinal plexuses, into which the circulation of the spinal cord is drained, is due to the association of multiple abnormalities (stenoses, compressions, thromboses) on the major pathways of the caval and azygos system. The abnormalities, most of which are not known, are demonstrated by a special procedure, the cavo-spinal phlebography, and some of them are subjected to surgery.
Everybody here brings happiness, somebody by coming,others by leaving.  PPMS since 2000<br />
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Postby North52 » Wed Nov 10, 2010 2:54 pm

Very interesting finding. I came across a similar but more recent study done in 1999.

http://www.ncbi.nlm.nih.gov/pubmed/20088446

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