• In a poster presentation, Dr. Marian Simka and colleagues of Katowice, Poland presented findings from 331 people with MS who had previously been determined to meet criteria for CCSVI, who were evaluated for duration and severity of MS, fatigue and other factors. They found no correlation between the severity of venous obstacles and age or duration of disease. They reported that those with narrowed azygous veins tended to have the most aggressive clinical course. No controls were noted. (Abstract P641)
This is from ECTRIMS. After the recent research and discussions of whether CCSVI might be worse in cases of longer-term MS, it seems like a counterbalance to look at what Dr. Simka is finding. No correlation between severity of venous obstacles and age or duration of disease. That's what we'd expect to find, too, if CCSVI is a congenital malformation disease.
The finding that those with narrowed azyous veins had the most aggressive clinical course seems obvious as well, if it turns out that reflux in the azygous is most damaging to the nearby spine. The spine has less ability to rework and reroute and recover than the brain does, leading to more aggressive disease and mobility issues.