Squeakycat wrote:EJC, just happened on the following in the Endocrine Society review. It shows that you can safely take high doses as they are recommending in certain situations. These are doses designed to raise low levels, not daily maintenance doses:Alternative strategies for nursing home residents include 50,000 IU of vitamin D 2 three times per week for 1 month (134) or 100,000 IU of vitamin D every 4 months (61).
That works out to a daily equivalent of 21,428 IU every day for a month.
NHE wrote:That's vitamin D2 which is ergocalciferol. It's less effective than vitamin D3 which is cholecalciferol. Therefore higher doses of D2 might be needed to achieve a similar effect compared to D3.
MarkW wrote:I use iHerb.com in California, USA for supply of Vit D3 5,000iu as high strength are not available in UK and many countries in Europe. Many brands of D3 are stocked by iHerb (http://www.iherb.com/Vitamin-D-5000-IU).
My iHerb code- WAL561 -is now worth $10 off for anyone shopping at iHerb for the 1st time. You will save $10 off your 1st iHerb purchase of $40 or more! Or $5 off on smaller orders.
You may find D3 cheaper (please let me know if you do). iHerb ships to Europe, but remember you may have to pay local sales tax (VAT is 20% in UK).
I will not benefit from anyone using this code as all discounts I receive are passed on to pwMS at OMSTC (http://www.omstc.org).
Squeakycat wrote:NHE wrote:That's vitamin D2 which is ergocalciferol. It's less effective than vitamin D3 which is cholecalciferol. Therefore higher doses of D2 might be needed to achieve a similar effect compared to D3.
Citations please? I have been looking at some contradictory studies on this as well as calcitriol which is being used in a lot of the cancer trials.
MarkW wrote:My logic of taking 5,000 iu a day stems from human evolution. Humans (spreading out from East Africa) were hunter-gatherers then farmers who lived in sunlight for much of their lives. They received Vit D3 (not D2) from sunlight in a fairly even manner.
MarkW wrote:I realise that buying D3 in an oily form (helps adsorption) is not easy in many countries including the UK so I posted the info below.
NZer1 wrote:So ethnicity will have an effect as much as location on the Planet. Down under we have a higher risk from Sun exposure because of all sorts of things from clearer skies to sun angles.
EJC wrote:I found a firm on eBay UK selling the brand you mentioned earlier in this thread.
I ordered a 360 day supply of the Healthy Origins Product in 10,000 iu liquicaps for £31 incl delivery.
The 5000iu caps are £14.96 + P&P
I do need to know what multivitamins/minerals Emma should be balancing this with though.
NZer1 wrote:MS Australia is running the world first randomised controlled trial to see if Vitamin D can actually prevent MS after an initial incident, there are different dose levels being trialled so some clarity might come from that :
http://www.msra.org.au/australia-rolls- ... tion-trial
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