NZer1 wrote:Ed my understanding from the article was that the VDR dysregulation is a deciding factor in the Vit D stats.
Whether you see the issue as primary by bacterial modification through a process of DNA modifying within immune and other cells or as the primary being Gene expression without bacterial invasion, or for that matter the outcome being determined by the two factors synergistically?
MarkW wrote:FIRST STEP TAKE VITAMIN D3 - 5000iu a day.
I started this very simple advice because the majority of pwMS have less than ideal levels of Vit D3. This dose of D3 is highly unlikely to cause any problems in pwMS. This is my researched professional opinion. If you have spent a significant amount of money on de-stenosis it is essential for immune and vein health to have a minimum Vit D3 blood level of 125mmol/L (50ng/ml). Taking Vit 3 is also much cheaper than de-stenosis.
There is a lot of very good advice on this thread about steps 2, 3, 4, etc. Please do not distracted by these later steps and miss the first step. There are pwMS who cannot have their level of D3 and essential minerals checked. Then steps 2 onwards are not possible but STEP ONE is essential and costs less than 50 USD per year.
The depth of background on this thread is wonderful, please keep on posting.
jimmylegs wrote:yeah 5000 IU per day was my first step originally too. worked great, right up until it caused my magnesium deficiency. what with the severe dysphagia and breathing difficulties, thought i was going to die - until a helpful pharmacist nudged me in the magnesium direction. what a lifesaver!
jimmylegs wrote:np. and yes you can certainly overdo these things. unfortunately, afaic, if you megadose without bloodwork, you're playing with fire. i've been playing with fire even with bloodwork, and have been occasionally burnt. c'est la vie in this game :S
Squeakycat wrote:MarkW wrote:FIRST STEP TAKE VITAMIN D3 - 5000iu a day.
I started this very simple advice because the majority of pwMS have less than ideal levels of Vit D3. This dose of D3 is highly unlikely to cause any problems in pwMS.
The modified version of this is take 5,000 IU/day of vitamin D3, or if you are south of the 35th parallel spend 20 minutes in the sun around noon each day which will provide 20,000 IU a day. Sunlight is as vital to human health as air and water.
NZer1 wrote: is there a situation where zinc, magnesium and calcium can be supplemented to high?
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