Cece wrote:There has been much talk about CCSVI's effect on oxygenation of the brain, I always want to pipe up and say don't forget about the glucose needs of the brain too. That too is likely depleted when outflow is blocked.
Some previous thinking on fast improvements was that it could be placebo, vascular in nature, or autonomic nervous system (?). Also if fatigue is lifted, then that can account for some improvement too possibly, such as being able to walk farther than before.
A big difference is if the neurons are "merely" damaged or undernourished, they can be restored, but if the neurons are gone, then they can't be brought back.
this matches my own experience. I can go for about half an hour, and then the legs just stop. then I have to sit down and rest a bit, eat an apple or drink a glass of coke. after, I can go again perhaps for 15 or 20 mins. taking a bit of sugar makes the hell of a difference. this has been the case many years now.
as you say, the implications of this could be BIG!! and indeed would seem to point at another mechanism than neuron death that explains the effect. a low glucose level because of slow blood flow would seem a plausible explanation. whow Cece, you have just given me an extra dose of hope..