Does the Azygos have a high or low restenosis rate?

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Does the Azygos have a high or low restenosis rate?

Postby dc10 » Fri Dec 17, 2010 10:51 am

Ive tried searching the forums but cant find a specific title on this,

I think i read somewhere earlier in the year saying how the Azygos is less prone to restenosis

is this true?

will ballooning alone of the azygos be sufficient for long term dilation?
have there been many cases of azygos restenosis?
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Re: Does the Azygos have a high or low restenosis rate?

Postby muse » Fri Dec 17, 2010 1:02 pm

dc10 wrote:I think i read somewhere earlier in the year saying how the Azygos is less prone to restenosis is this true?

The rate of a restenoses in the V. azygos is very low, about 4%. Check out the "Bologna protocol"

will ballooning alone of the azygos be sufficient for long term dilation? have there been many cases of azygos restenosis?


1.Yes & 2.No.
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Postby dc10 » Fri Dec 17, 2010 1:22 pm

thats great then,

My mid-azygos had a high grade (95%) stenosis, which was dilated with a balloon up to 10mm in a step-by-step technique.

maybe i will be in the unlucky 4%
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Postby Cece » Fri Dec 17, 2010 3:01 pm

I've heard that the azygous is less likely to restenose, and Dr. Zamboni has at least one paper showing this, but I have my doubts. (Sorry, dan, nothing personal ;) ) But why would the azygous vein be different than the other veins? If it's a valve malformation, that's just as likely to pop back out.
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Postby muse » Fri Dec 17, 2010 3:23 pm

Cece wrote:I've heard that the azygous is less likely to restenose, and Dr. Zamboni has at least one paper showing this, but I have my doubts. (Sorry, dan, nothing personal ;) ) But why would the azygous vein be different than the other veins? If it's a valve malformation, that's just as likely to pop back out.


Zamboni et al: http://www.fondazionehilarescere.org/pdf/CX.PDF

Bologna protocol by J. Beal: http://www.facebook.com/note.php?note_i ... 210&ref=mf

Dr. Roberto Galeotti, Azienda Ospedaliero- Universitaria di Ferrara, vascular surgeon speaks as to the results of the endovascular Liberation treatment in an open label CCSVI study.: “….The azygos vein had a 4% rate of restenosis at 18 months- the only case was a retwisting. The jugular veins had a rate of 47% of restenosis at 18 months. The team is considering a redilation of the IJVs using open neck surgery or stents….”
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Postby Cece » Fri Dec 17, 2010 3:49 pm

I've read that Dr. Zamboni and Dr. Galeotti found that the azygous was not restenosing, but I don't understand the reasoning for it.

Perhaps they were treating more of the membraneous types of CCSVI in the azygous.

With the azygous being smaller, perhaps their 10 mm balloon size did a better job of breaking the "annular constriction" in the azygous that the 10 mm balloons did in the IJVs.
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Postby sou » Fri Dec 17, 2010 5:43 pm

The azygos is narrower and "stabler" than the IJVs. The latter do not have a fixed diameter, but it depends on the position of the head, the bending of the neck etc. This could be related to a venous wall of different mechanical and/or chemical properties that make them prone to restenosing.
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Postby NotFound » Fri Dec 17, 2010 6:07 pm

I guess it also depends on the nature of stenosis.

Mine was twisted about itself (>90% occlusion) and re-twisted right back after several ballooning attempts.
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Postby dc10 » Sun Dec 19, 2010 3:49 am

thank for the links/info
hopefully my azygos wont restenose :)
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