I believe that this discussion should not concentrate exclusively on the vascular dimension. The reason why we have taken this discussion so far is that we have been able and willing to look outside the box, that is the box of the neurologists. Now we should not make the systemic failure of locking ourselves into the vascular box. Our primary goal must be to solve the mystery of MS, to find what causes MS and how to best treat it.
Therefore, we must keep our eyes open and continue to look broader, for instance into the low-glucose hypothesis. In fact, MS is a complex disease that to solve it, besides neurologist and vascular doctors, may need to involve other disciplines such as diabetics specialists.
In the beginning of the 1980's there has been a discussion about the links between MS and diabetes. But it was difficult to prove and the issue disappeared in the background. Now with this new ccsvi condition, perhaps the old discussion of the 1980s should be held again, in the right context and against this new background. For further information about the low glucose condition, see: http://www.thisisms.com/ftopict-15181.html
I think the medical world can not get around this low-glucose hypothesis. The explanation given for the double peak in the age of onset makes this highly plausible as a concept. For the rest of the posting, if you do google and bing searches, you will find many recent articles that can confirm every single sentence of the (hypo)thesis.
Therefore, I call on the medical world to investigate the low-glucose hypothesis as part of their efforts. They can deny, deter, defer, delay and try to destroy. But at the end of the day, that will not work because the evidences are there and the pieces of the puzzle just connect too neatly.